Efficacy of Aleo Vera Use in Prevention and Treatment of Chemotherapy-Induced Oral Mucositis in a Group of Egyptian Children with Acute Leukemia
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 40
- 试验地点
- 1
- 主要终点
- Prevention of oral mucositis
研究概览
简要总结
evaluatation the efficacy of Aleovera in prevention and treatment of chemotherapy-induced oral mucositis in children suffering from acute leukemia in terms of appearance and severity
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Prevention
- 盲法
- None
入排标准
- 年龄范围
- 3 Years 至 13 Years（Child）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Patients suffering from Acute leukemia( Acute Lymphocytic Leukemia ).
- •Patients scheduled for chemotherapy treatment.
- •Patients who range from 3 to 13 years old.
- •Patients with no history of any chemotherapy or radiotherapy. 5 -Both sexes
排除标准
- •1-Patients scheduled for radiotherapy treatment . 2-Existence of any signs or symptoms of oral mucositis. 3-Unwilling to participation in the study 4- Patients with any other systemic diseases or other neoplasms.
研究组 & 干预措施
Alovera experminted arm
干预措施: Second arm: Using aleovera for Prevention and Treatment of Chemotherapy-Induced Oral Mucositis (Other)
second group
结局指标
主要结局
Prevention of oral mucositis
时间窗: 2 months
Assessment the efficacy of aleo vera gel on prevention of chemotherapy-induced oral mucositis through application the gel 3 times daily then patients were assessed daily in terms of appearance and severity of oral mucositis according WHO grading system. The World Health Organization (WHO) mucositis scale is used to grade the severity of oral mucositis. Grade 0: No mucositis Grade 1: Soreness/erythema only. Grade 2: Erythema, and ulcers. Able to tolerate solids. Grade 3: Unable to tolerate solids but able to tolerate liquids. Grade 4: Unable to tolerate solids or liquids. Oral alimentation is not possible.
次要结局
未报告次要终点