Position Of The Tip Of The Inner Catheter And Air Bubbles As Predictors Of Pregnancy During ICSI Cycles:Prospective Observational Study
试验速览
- 阶段
- 不适用
- 入组人数
- 94
- 主要终点
- clinical pregnancy rate
研究概览
简要总结
Position of the tip of the inner catheter and air bubbles detection (at time,5min 10min)during embryo transfer influence the pregnancy rate in ICSI cycles .
详细描述
The aim of this study is to assess the relationship between the position of the tip of the inner catheter, the position of the air bubbles (at time , 5 min ,10 min )after embryo transfer and pregnancy rate outcome in ICSI cycles. Most IVF teams consider not touching the endometrium and the uterine fundus with replacement of the embryos in the lumen of the endometrial cavity the most important factors for successful embryo transfer, it is highly recommended to use agents that can facilitate a smooth embryo transfer and reduce unintended stimulation of the fundus, for example the application of soft-tipped catheters, which can improve pregnancy rate.
The advantage of using the air and liquid content for catheter loading is to prevent the embryo from adhering to the wall of the catheter at the time of injection.The presence of two air bubbles on both sides of the medium that contains the embryo prevents the transfer of the embryo within the catheter and beside, in the transfer under ultrasonographic guidance, the air bubbles are often considered a marker for the embryo's position in the uterus.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 20 Years 至 40 Years(Adult)
- 性别
- Female
- 接受健康志愿者
- 是
入选标准
- •BMI < 30 kg/ m
- •Between 20 and 35years old.
- •FSH levels on cycle day 3 of <12 mIU/mL.
- •Both ovaries present deprived of morphological abnormalities and adequately visualized in Transvaginal ultrasound.
- •Grade one or two embryo quality.
排除标准
- •Hydrosalpinx.
- •Intrauterine lesion.
- •Patients undergoing ET after cryopreservation.
- •Blood present on the catheter during the transfer procedure.
- •A difficult transfer or with a suspicion of touching the fundus.
- •Endometrial thickness less than 8mm.
- •Known allergic reaction against one of the ingredient of the medications used during the study.
结局指标
主要结局
clinical pregnancy rate
时间窗: one and half year
次要结局
未报告次要终点
研究者
AMR HELMY YEHIA
Associate Professor
Ain Shams Maternity Hospital
