The Role of Postoperative Antibiotics in Laparoscopic Cholecystectomy

Phase 4

Recruiting

• Conditions: Infection Wound; Antibiotic Resistant Infection
• Interventions: Drug: IV antibiotic; Drug: Oral antibiotic

• Registration Number: NCT06607887
• Lead Sponsor: Minia University Hospital

Brief Summary

Comparison between postoperative parenteral prophylactic antibiotics, and oral antibiotics regarding the incidence of post laparoscopic cholecystectomy infection.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-08-30
• Status Verified: 2024-09
• Study First Submitted: 2024-09-19
• Study First Submitted QC: 2024-09-19
• Last Update Submitted: 2024-09-19
• Study First Posted: 2024-09-23
• Last Update Posted: 2024-09-23
• Primary Completion: 2024-11-30
• Study Completion: 2024-12-30

Recruitment & Eligibility

• Status: RECRUITING
• Sex: All
• Target Recruitment: 300

Inclusion Criteria

• Adult patients (aged above 18 years) undergoing laparoscopic cholecystectomy.

Exclusion Criteria

• patients with comorbidities (Diabetes, malignancies, Immunosuppressed). Lost of follow-up. Patients received antibiotics within 72 hr before admission. Complicated cases involved, gangrenous and perforated cholecystitis and abscess.

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
IV antibiotic	IV antibiotic	-
Oral Antibiotic	Oral antibiotic	-

Primary Outcome Measures

Name	Time	Method
Surgical site infection	4 weeks	DSSI = deep surgical site infection; SSSI = superficial surgical site infection.

Secondary Outcome Measures

Name	Time	Method
Length of the hospital stay	4 weeks
Hematoma and Seroma formation	4 weeks
Fever	4 weeks

Trial Locations

Locations (1)

Minia University Hospital; 🇪🇬 Minya, Egypt