A comparison of return of gastrointestinal function between oxygen content guided goal-directed therapy and standard fluid therapy in major abdominal surgery patients: A prospective randomized controlled study

Phase 2

Completed

• Conditions: The return of gastrointestinal function and blood lactate between oxygen content guided goal-directed therapy and standard fluid therapy in major abdominal surgery patients; Oxygen content; Goal directed therapy; Major abdominal surgery patients

• Registration Number: TCTR20210204006
• Lead Sponsor: Maharaj Nakorn Chiang Mai Hospital

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2020-10-25
• Study Start: 2021-02-04
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 70

Inclusion Criteria

Age > 18 years old
Elective open major abdominal surgery
Estimated blood loss >500 ml
Expected operative time >120 min

Exclusion Criteria

Patients refuse consent
Gynecological surgery
Trauma
Septicemia
Heart failure
Cardiac arrhythmia
Poor peripheral circulation
Patient on pacemaker
Aortic valvular disease
Rapid high blood pressure from the vasoactive drug (Phenylephrine, Nicardipine)
esCCI < 2.5 L/min/m2
Renal impairment (CKD 4, 5)

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Return of gastrointestinal function Post operation daily Auscultation of bowel sound

Secondary Outcome Measures

Name	Time	Method
evel of lactate Before and end of surgery Blood,Length of stay Post operation Day