ISRCTN98495886已完成2 期
Phase II clinical trial investigating the use of EPIgallocatechin-3-gallate (Veregen) in the treatment of Vulval Intraepithelial Neoplasia
niversity of Birmingham (UK)0 个研究点目标入组 26 人开始时间: 2013年12月17日最近更新:
适应症
试验速览
- 阶段
- 2 期
- 状态
- 已完成
- 发起方
- 入组人数
- 26
研究概览
简要总结
2020 Results article in https://pubmed.ncbi.nlm.nih.gov/33075197/ results (added 18/11/2020)
研究设计
- 研究类型
- Interventional
入排标准
- 性别
- Female
入选标准
- •1. Female = 18 years of age
- •2. Histological confirmation of 'usual' type vulval intraepithelial neoplasia (VIN3)*
- •3. At least one lesion that can be accurately measured (using the RECIST 1.1 criteria) in at least one dimension with longest diameter = 20 mm
- •4. Using a reliable method of contraception (excluding condoms)
- •5. Written informed consent to participate in the trial
- •* All histological material generated by this study will be assessed by Specialist Consultant in Gynaecological Pathology, 10% of biopsies will be independently reviewed by a second pathologist
排除标准
- •1. Suspected anogenital carcinoma or those considered by the attending clinician to be at high risk of developing invasive disease
- •2. Pregnant, breastfeeding or trying to conceive
- •3. Treated for VIN within the previous four weeks
- •4. Known allergy to Veregen or any of its components
- •5. Patients suffering from immunosuppressive disorder or taking immunosuppressives
- •6. Unable to comply with the protocol
研究者
相似试验
进行中（未招募）
1 期
A phase I/II study to determine efficacy, safety and immunogenicity of the candidate coronavirus disease (COVID-19) vaccine ChAdOx1 nCoV-19 in UK healthy adult volunteersCOVID-19 (SARS-CoV-2 infection)Infections and InfestationsISRCTN15281137niversity of Oxford1,077
已完成
不适用
An early tailored cognitive behavioural therapy intervention for depression in individuals newly diagnosed with multiple sclerosisMild to moderate depression among individuals newly diagnosed with MSMental and Behavioural DisordersISRCTN63987586Multiple Sclerosis Research Australia60
进行中（未招募）
2 期
Investigating a vaccine against COVID-19COVID-19 (SARS-CoV-2 infection)Infections and InfestationsISRCTN90906759niversity of Oxford12,390
进行中（未招募）
2 期
Radiotherapy combined with immunotherapy in metastatic non-small cell lung cancer patientsAdvanced non-small cell lung cancer, stage IVMalignant neoplasm the lung, non-small cell lung cancerCancerISRCTN49817477Maastricht University88
终止
2 期
apatinib plus capecitabine versus continued trastuzumab plus capecitabine after local therapy in patients with ErbB2-positive metastatic breast cancer developing brain metastasis/esBreast cancer, developing brain metastasis/esBreast cancerCancerISRCTN58771616eeds Teaching Hospitals NHS Trust (UK)30