The Influence of Corticosteroid Treatment on Heart Function

• Conditions: Myocardial Function
• Interventions: Other: Transthoracic Echocardiogram

• Registration Number: NCT02232048
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

Patients hospitalized in internal medicine departments are given corticosteroid treatment according clinical indications. Patients receive treatment at different dosage levels and in different preparations according to clinical indications. This study will investigate how corticosteroids effect the heart and specifically, longitudinal strain.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2014-08-20
• Status Verified: 2014-09
• Study Start: 2014-09
• Study First Submitted QC: 2014-09-02
• Study First Posted: 2014-09-04
• Last Update Submitted: 2014-09-08
• Last Update Posted: 2014-09-09
• Primary Completion: 2016-09
• Study Completion: 2016-09

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 100

Inclusion Criteria

• Stable patients able to undergo Transthoracic Echocardiogram
• Patients beginning treatment with corticosteroids

Exclusion Criteria

• Pregnant
• Patients recently or chronically treated with corticosteroids

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Corticosteroid Treatment	Transthoracic Echocardiogram	Patients in the internal medicine department who are being treated with corticosteroids will undergo Transthoracic Echocardiogram to determine change in heart function.

Primary Outcome Measures

Name	Time	Method
Change in Heart Function	Two years	Heart contraction and specifically its longitudinal strain will be examined using Transthoracic Echocardiogram (TTE) before, during and after corticosteroid treatment. TTE reveals changes in contraction in the right and left ventricle and septum.

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 Hadera, Israel