Validation of biomarkers for Crohn*s disease using peripheral blood cells of patients

Recruiting

Conditions: crohn's disease
Inflammatory bowel disease
ulcerative colitis
10017969
10003816

Registration Number: NL-OMON48615

Lead Sponsor: Vrije Universiteit Medisch Centrum

Brief Summary: Not available

Detailed Description: Not available

Recruitment & Eligibility

Status: Recruiting

Sex: Not specified

Target Recruitment: 200

Inclusion Criteria

Patients:
- Provide informed consent
- Within age 18 until 75
- Diagnosed with Crohn*s disease or ulcerative Colitis
Healthy volunteers:
- Provide informed consent
- Within age 18 until 75
- Healthy, without a medical history of any inflammatory disease

Exclusion Criteria

-Patients:
- Younger than 18 and older than 75
- Patients who cannot be properly informed about the risks due to an
insufficient ability to speak Dutch or English
- History of another inflammatory diseaseHealthy volunteer:
- History of any inflammatory disease
- Younger than 18 and older than 75
- Employees of the department of Gastroenterology
- Family or friends of employees of the department of Gastroenterology

Study & Design

Study Type: Observational invasive

Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
<p>Definition of final staining panel which can allow for early inflammation<br /><br>dectection as well as distinguish between various forms of IBD , using<br /><br>peripheral blood samples. </p><br>

Secondary Outcome Measures

Name	Time	Method
<p>1. Whether with this peripheral blood test a flare can be predicted<br /><br>2. Whether this peripheral blood test can distinguish CD from UC patients.<br /><br>3. To see how the medication of IBD patients can affect immune cell activation<br /><br>markers within peripheral blood.</p><br>