Protocol for Evaluating Physiological and Psychological Adaptation Mechanisms in Tibetan Plateau Environments

• Conditions: High Altitude
• Interventions: Other: measurement

• Registration Number: NCT06557928
• Lead Sponsor: Peking Union Medical College Hospital

Brief Summary

This study is a single-center prospective observational study. It plans to use a series of physiological and medical instruments and international common physiological and psychological questionnaires. To dynamically detect the changes of physiological and psychological adaptability of doctors in Peking Union Medical College Hospital before leaving Beijing, 1-7 days after arriving at the plateau in Tibet during the acute phase of plateau hypoxic stress, 2 weeks, 3 months, 6 months, 12 months after staying in Tibet during the chronic phase of plateau hypoxic stress, and after returning to Beijing.

Detailed Description

Not available

Study Timeline

• Study Start: 2024-05-17
• Status Verified: 2024-08
• Study First Submitted: 2024-08-14
• Study First Submitted QC: 2024-08-14
• Last Update Submitted: 2024-08-14
• Study First Posted: 2024-08-16
• Last Update Posted: 2024-08-16
• Primary Completion: 2026-12-01
• Study Completion: 2027-12-01

Recruitment & Eligibility

• Status: ENROLLING_BY_INVITATION
• Sex: All
• Target Recruitment: 17

Inclusion Criteria

• Healthy individuals aged 20-65 years
• They can sign a written informed consent and is willing to cooperate
• They have the qualification to aid Tibet and meet the basic requirements of physical examination for aid to Tibet

Exclusion Criteria

• Age less than 20 years or more than 65 years
• Unable to sign a written informed consent or unwilling to cooperate
• They do not have the qualification for supporting Tibet or do not meet the basic requirements of medical examination for supporting Tibet

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Arm && Interventions

Group	Intervention	Description
Doctors to Tibet from Peking Union Medical College Hospital in 2024	measurement	-
Doctors to Tibet from Peking Union Medical College Hospital in 2025	measurement	-

Primary Outcome Measures

Name	Time	Method
help understand the physiological mechanisms and psychological changes of hypoxic adaptation	2024-5-27~2026-12-1	This study is expected to increase our understanding of the physiological mechanisms and psychological changes of hypoxic adaptation mainly through analysis of multi-omics.

Trial Locations

Locations (1)

Peking Union Medical College Hospital; 🇨🇳 Beijing, China