Protocol for Evaluating Physiological and Psychological Adaptation Mechanisms in Tibetan Plateau Environments: A Clinical Study of Doctors From Peking Union Medical College Hospital
试验速览
- 阶段
- 不适用
- 状态
- Enrolling By Invitation
- 入组人数
- 17
- 试验地点
- 1
- 主要终点
- help understand the physiological mechanisms and psychological changes of hypoxic adaptation
研究概览
简要总结
This study is a single-center prospective observational study. It plans to use a series of physiological and medical instruments and international common physiological and psychological questionnaires. To dynamically detect the changes of physiological and psychological adaptability of doctors in Peking Union Medical College Hospital before leaving Beijing, 1-7 days after arriving at the plateau in Tibet during the acute phase of plateau hypoxic stress, 2 weeks, 3 months, 6 months, 12 months after staying in Tibet during the chronic phase of plateau hypoxic stress, and after returning to Beijing.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Only
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 50 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Healthy individuals aged 20-65 years
- •They can sign a written informed consent and is willing to cooperate
- •They have the qualification to aid Tibet and meet the basic requirements of physical examination for aid to Tibet
排除标准
- •Age less than 20 years or more than 65 years
- •Unable to sign a written informed consent or unwilling to cooperate
- •They do not have the qualification for supporting Tibet or do not meet the basic requirements of medical examination for supporting Tibet
结局指标
主要结局
help understand the physiological mechanisms and psychological changes of hypoxic adaptation
时间窗: 2024-5-27~2026-12-1
This study is expected to increase our understanding of the physiological mechanisms and psychological changes of hypoxic adaptation mainly through analysis of multi-omics.
次要结局
未报告次要终点
研究者
DONG WU
Professor of Gastroenterology
Peking Union Medical College Hospital