A Multi-Disciplinary Evaluation of Home-Based High-Intensity Interval Training in People With Type 1 Diabetes: A Pilot Study
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 11
- 试验地点
- 2
- 主要终点
- Compliance over the course of the training programme
研究概览
简要总结
This study aimed to use a multi-disciplinary approach to evaluate a 6-week home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
详细描述
This study aimed to use a multi-disciplinary approach to evaluate a home-based high-intensity interval training (Home-HIT) intervention in people with type 1 diabetes.
Eleven individuals with type 1 diabetes (4 men/7 women; age 30±3 years; BMI 27.1±1.2 kg·m-2; V ̇O2peak 32.4±2.1 ml∙kg∙min-1; duration of type 1 diabetes 10±2 years) completed six weeks of Home-HIT. The effect of Home-HIT on V ̇O2peak, blood pressure, insulin dose and glycaemic profile was assessed pre and post-training. Adherence and ability to meet target heart rate (HR) thresholds (compliance) were monitored using a HR monitor and mobile phone application. Change in glycaemia was measured pre, post and 1h post exercise sessions throughout the six-week period. A qualitative online survey was completed post-training.
This is the first study to combine physiological outcomes with a qualitative evaluation of a training intervention in people with type 1 diabetes. Home-HIT resulted in high adherence alongside increased V ̇O2peak and decreased insulin dose. Because Home-HIT is time-efficient and removes barriers to exercise including fear of hypoglycaemia, it may represent an effective strategy to increase exercise participation in people with type 1 diabetes.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 55 Years（Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •duration of type 1 diabetes >6 months,
- •no significant history of hyper- or hypoglycaemia
排除标准
- •duration of type 1 diabetes <6 months,
- •significant history of hyper- or hypoglycaemia,
- •pregnancy or planning pregnancy,
- •uncontrolled hypertension (>180/100 mmHg),
- •autonomic neuropathy,
- •taking any medication that affects heart rate (HR)
- •major surgery planned within 6 weeks of the study
- •severe nonproliferative
- •unstable proliferative retinopathy
结局指标
主要结局
Compliance over the course of the training programme
时间窗: compliance to the training programme over the course of the 6 week intervention
ability to meet target heart rates (compliance) was assessed
adherence over the course of the training programme
时间窗: adherence to the training programme over the course of the 6 week intervention
session completion rate (adherence) was assessed
change in maximal aerobic capacity
时间窗: change in baseline maximal aerobic capacity at 6 weeks
Maximal aerobic capacity was measured pre and post 6 week training intervention using a MOXUS gas analyser on a stationary cycle ergometer
次要结局
- change in insulin sensitivity(change in baseline insulin sensitivity at 6 weeks)
- change in glycaemic control(change in baseline glycaemic control at 6 weeks)
研究者
Sam Shepherd
Lecturer/Senior Lecturer, Principle Investigator
Liverpool John Moores University