The Women's Hormone Intervention Secondary Prevention Pilot Study

Medical Research Council (MRC) (UK)0 个研究点目标入组 125 人开始时间: 2000年10月25日最近更新: 2015年1月13日

适应症

试验速览

暂无简介。

•Post menopausal women (amenorrhoea for more than 12 months oestrogen deficiency symptoms) or more than 55 years, more than 48 hours and less than 7 days after the onset of acute Myocardial Infarction (MI) (Creatine Kinase [CK] twice upper limit or CKMB above the threshold considered diagnostic for myocardial damage in that centre) plus one of the two additional following criteria:
•1. Admission for symptoms of acute myocardial ischaemia
•2. Changes on the electrocardiogram supportive of a diagnosis of acute MI, provision of written informed consent

•1. Unconfirmed MI
•2. Use of HRT currently or previous 12 months, patients for whom clear indications for, of contraindications to, long term HRT
•3. Increased risk of thromboembolism
•4. Prior history of DVT or PE
•5. BMI more than 32
•6. Prolonged immobility
•7. Known breast or endometrial cancer
•8. Post-menopausal bleeding that has not been adequately investigated
•9. Presence of non-cardiac condition influencing survival
•10. Anticipated inability of the patient to comply with the study procedures

发起方

Medical Research Council (MRC) (UK)