Can Pregnancy be Predicted According to ATR-FTIR Spectrophotometry of Incubation Medium of Embryos in IVF

• Conditions: Infertility

• Registration Number: NCT03317418
• Lead Sponsor: Hillel Yaffe Medical Center

Brief Summary

The aim of this study is to examine the variability of culture media composition based on the ATR-FTIR (Attenuated Total Reflectance-Fourier Transform Infrared Spectroscopy) technique on the day of embryo transfer/vitrification. In addition, the study will explore whether variations detected in the culture medium can be linked to embryo quality and the chances of achieving pregnancy.

Detailed Description

Not available

Study Timeline

• Study First Submitted: 2017-10-18
• Study First Submitted QC: 2017-10-18
• Study First Posted: 2017-10-23
• Study Start: 2017-11-01
• Status Verified: 2022-06
• Last Update Submitted: 2022-06-22
• Last Update Posted: 2022-06-23
• Primary Completion: 2023-11
• Study Completion: 2023-11

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: Female
• Target Recruitment: 100

Inclusion Criteria

• Women undergoing IVF treatments with at least 4 embryos

Exclusion Criteria

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Spectrometry in embryo culture media	One year	Definition of spectrometry in embryo culture media
Embryo quality	One year	The spectrometry results will be linked to embryo quality through the linkage between spectrometry results as indicated on Absorbance Graph and embryo quality judged by accepted criteria

Secondary Outcome Measures

Name	Time	Method
Cycle outcomes	One year	Prediction of pregnancy rates as linked to the spectrometry results of the culture media

Trial Locations

Locations (1)

Hillel Yaffe Medical Center; 🇮🇱 H̱adera, Israel