KCT0003115尚未招募未知
Effectiveness and safety of Ojeok-san plus Saengmaek-san for chronic cough - a randomized, double-blind, placebo-controlled, parallel, single center and investigator-initiated clinical trial
Kyung Hee University Oriental Medical Center0 个研究点目标入组 30 人开始时间: 待定最近更新:
适应症
试验速览
- 阶段
- 未知
- 状态
- 尚未招募
- 发起方
- 入组人数
- 30
研究概览
简要总结
暂无简介。
研究设计
- 研究类型
- Interventional Study
入排标准
- 年龄范围
- 19(Year) 至 69(Year)（—）
- 性别
- All
入选标准
- •1) Only 19 years old and under 70 years old
- •2) Persons who have continued coughing for more than 8 weeks
- •3) who have been diagnosed with reflux esophagitis within the last 1 year
- •4) In case of patient,
排除标准
- •1) Those with abnormal findings that could cause cough as a result of chest x-ray
- •2) Those with abnormal findings in lung function tests
- •3) Those with evidence of coughing on nasal endoscopy
- •4) Those who have been diagnosed with acute respiratory disease including upper respiratory tract within the last 1 month
- •5) Those who have been diagnosed with chronic respiratory diseases (chronic obstructive pulmonary disease, bronchial asthma, bronchiectasis, interstitial pulmonary disease and other chronic respiratory diseases) within the last 2 years
- •6) who have been diagnosed gastroesophageal reflux disease of LA grade C or higher within the last 1 year
- •7) Patients who present with symptoms that can predict the malignant disease of the gastrointestinal tract (swallowing, severe dysphagia, bleeding, weight loss, anemia, stool, etc.)
- •8) Patients who had previously undergone surgical or endoscopic anti-reflux treatment
- •9) Patient with Hubiru syndrome
- •10) Patients with active infection requiring systemic antibiotic treatment
- •11) Patients with blood clotting disorder
- •12) Those who smoke more than 20 packs (400 packs)
- •13) Those who have been taking or have taken an angiotensin-converting-enzyme inhibitor within the last 4 months
- •14) Those who have been taking chronotherapy, steroids, anti-leukotrienes, anticholinergics, long-acting ß2 agonists, and any herbal medicines within the last 2 weeks
- •15) Those taking antihistamines within the last 2 weeks
- •16) Those who have taken proton pump inhibitors, histamine receptor antagonists, mucosal protective agents, gastrointestinal motility promoters, antacids, antidepressants, anxiolytics, and lower esophageal sphincter agonists for the treatment of gastroesophageal reflux disease symptoms within the last 2 weeks
- •17) Allergy or sensitizer to test drug / placebo
- •18) Those with a low birth weight below 18.5 on the BMI
- •19) Blood test results showed that AST and ALT were 2 times higher than the normal upper limit and Creatinine was 1.2 times higher than the normal upper limit
- •20) Those with a mean cough diary of 2 or less during the run-in-period period (7 days)
- •21) who recorded less than 10 cough diaries during the run-in-period period (7 days)
- •22) Those who had malignant tumors such as lung cancer or esophageal cancer within 5 years
- •23) Excessive drinking
- •24) Those who are pregnant or lactating
- •25) Those who did not consent to contraception during the clinical trial
- •26) Patients who participated in clinical trials for the same disease within the past 3 months
- •27) Those who are not eligible to take part in this trial at the discretion of the investigator
研究者
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