Early Nutrition Impact on Post Abdominal Surgery Outcome
- Conditions
- Postoperative Nutrition
- Interventions
- Dietary Supplement: postoperative nutrition
- Registration Number
- NCT04567641
- Lead Sponsor
- Cairo University
- Brief Summary
Introduction: Nutritional support is a vital therapy of most surgical patients. Early initiation via the enteral route has a significant effect on postoperative recovery. The prognostic role of CRP and albumin can be explained by their abilities to reflect inflammation in the acute phase in critical settings and assess the nutritional status of critically ill patients, respectively. This indicates the prognostic value of the CRP/ALB ratio in postoperative patients admitted to the ICU.
Aim of work: Determine the effect of early enteral \& parenteral nutrition on ICU outcome \& nutritional status in postoperative abdominal surgical patients and investigate the effect of enteral \& parenteral nutrition on CRP/albumin ratio as an inflammatory marker \& its correlation with SOFA score.
Methods: A prospective cohort non randomized study included 80 postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration. Forty patients (50%) received enteral nutrition 6 hours after surgical procedures and 40 patients (50%) received parenteral nutrition 6 hours after surgical procedures. Nutritional status and inflammatory markers were screened. All patients were followed up during the ICU stay \& up to 3 months. SOFA scoring was done every 48 hours.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 80
- postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration.
- age between 18-80 years
- renal failure
- liver failure
- extensive burns
- hemodynamic instability.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description Enteral Nutrition postoperative nutrition - Parenteral nutrition postoperative nutrition -
- Primary Outcome Measures
Name Time Method duration of mechanical ventilation. 7 days measurement of days of mechanical ventilation
Gastro-intestinal tolerance: vomitting or diarrhea 7 days number of participants who develop nausea, vomitting or diarrhea
Refeeding syndrome; hypokalemia and hypophosphatemia 7 days number of participants who develop hypokalemia and hypophosphatemia
length of ICU stay 7 days measurement of days of ICU stay
- Secondary Outcome Measures
Name Time Method 3 months survival after discharge . 90 days measurement of the rate of survival within 3 months between participants
re-admission within 30 days 30 days measurement of the rate of hospital re-admission within 30 days between participants