Impact of Early Enteral & Parenteral Nutrition on Post-operative Outcome After Abdominal Surgery
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Postoperative Nutrition
- Sponsor
- Cairo University
- Enrollment
- 80
- Primary Endpoint
- duration of mechanical ventilation.
- Status
- Completed
- Last Updated
- 5 years ago
Overview
Brief Summary
Introduction: Nutritional support is a vital therapy of most surgical patients. Early initiation via the enteral route has a significant effect on postoperative recovery. The prognostic role of CRP and albumin can be explained by their abilities to reflect inflammation in the acute phase in critical settings and assess the nutritional status of critically ill patients, respectively. This indicates the prognostic value of the CRP/ALB ratio in postoperative patients admitted to the ICU.
Aim of work: Determine the effect of early enteral & parenteral nutrition on ICU outcome & nutritional status in postoperative abdominal surgical patients and investigate the effect of enteral & parenteral nutrition on CRP/albumin ratio as an inflammatory marker & its correlation with SOFA score.
Methods: A prospective cohort non randomized study included 80 postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration. Forty patients (50%) received enteral nutrition 6 hours after surgical procedures and 40 patients (50%) received parenteral nutrition 6 hours after surgical procedures. Nutritional status and inflammatory markers were screened. All patients were followed up during the ICU stay & up to 3 months. SOFA scoring was done every 48 hours.
Investigators
Mostafa Farouk
clinical professor
Cairo University
Eligibility Criteria
Inclusion Criteria
- •postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration.
- •age between 18-80 years
Exclusion Criteria
- •renal failure
- •liver failure
- •extensive burns
- •hemodynamic instability.
Outcomes
Primary Outcomes
duration of mechanical ventilation.
Time Frame: 7 days
measurement of days of mechanical ventilation
Gastro-intestinal tolerance: vomitting or diarrhea
Time Frame: 7 days
number of participants who develop nausea, vomitting or diarrhea
Refeeding syndrome; hypokalemia and hypophosphatemia
Time Frame: 7 days
number of participants who develop hypokalemia and hypophosphatemia
length of ICU stay
Time Frame: 7 days
measurement of days of ICU stay
Secondary Outcomes
- 3 months survival after discharge .(90 days)
- re-admission within 30 days(30 days)