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Clinical Trials/NCT04567641
NCT04567641
Completed
Not Applicable

Impact of Early Enteral & Parenteral Nutrition on Post-operative Outcome After Abdominal Surgery

Cairo University0 sites80 target enrollmentJanuary 2017

Overview

Phase
Not Applicable
Intervention
Not specified
Conditions
Postoperative Nutrition
Sponsor
Cairo University
Enrollment
80
Primary Endpoint
duration of mechanical ventilation.
Status
Completed
Last Updated
5 years ago

Overview

Brief Summary

Introduction: Nutritional support is a vital therapy of most surgical patients. Early initiation via the enteral route has a significant effect on postoperative recovery. The prognostic role of CRP and albumin can be explained by their abilities to reflect inflammation in the acute phase in critical settings and assess the nutritional status of critically ill patients, respectively. This indicates the prognostic value of the CRP/ALB ratio in postoperative patients admitted to the ICU.

Aim of work: Determine the effect of early enteral & parenteral nutrition on ICU outcome & nutritional status in postoperative abdominal surgical patients and investigate the effect of enteral & parenteral nutrition on CRP/albumin ratio as an inflammatory marker & its correlation with SOFA score.

Methods: A prospective cohort non randomized study included 80 postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration. Forty patients (50%) received enteral nutrition 6 hours after surgical procedures and 40 patients (50%) received parenteral nutrition 6 hours after surgical procedures. Nutritional status and inflammatory markers were screened. All patients were followed up during the ICU stay & up to 3 months. SOFA scoring was done every 48 hours.

Registry
clinicaltrials.gov
Start Date
January 2017
End Date
January 2019
Last Updated
5 years ago
Study Type
Observational
Sex
All

Investigators

Responsible Party
Principal Investigator
Principal Investigator

Mostafa Farouk

clinical professor

Cairo University

Eligibility Criteria

Inclusion Criteria

  • postoperative abdominal surgical patients at Critical Care Department, Cairo University over one year duration.
  • age between 18-80 years

Exclusion Criteria

  • renal failure
  • liver failure
  • extensive burns
  • hemodynamic instability.

Outcomes

Primary Outcomes

duration of mechanical ventilation.

Time Frame: 7 days

measurement of days of mechanical ventilation

Gastro-intestinal tolerance: vomitting or diarrhea

Time Frame: 7 days

number of participants who develop nausea, vomitting or diarrhea

Refeeding syndrome; hypokalemia and hypophosphatemia

Time Frame: 7 days

number of participants who develop hypokalemia and hypophosphatemia

length of ICU stay

Time Frame: 7 days

measurement of days of ICU stay

Secondary Outcomes

  • 3 months survival after discharge .(90 days)
  • re-admission within 30 days(30 days)

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