Comparison of Sublingual Misoprostol and Intravenous Oxytocin in Active Management of the Third Stage of Labor
- Conditions
- Postpartum Hemorrhage Prevention by Using Oxytocin Verses Misoprostol
- Registration Number
- NCT01612390
- Lead Sponsor
- Rasha Mohammed Mohammed Badawi
- Brief Summary
Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor
- Detailed Description
Sublingual misoprostol is superior to oxytocin in reduction of blood loss during the third and fourth stages of labor as The data from a pharmacokinetics study suggested that the bioavaiblitiy of misoprostol after sub-lingual administration was higher than those after oral or vaginal administration
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 180
Inclusion Criteria
- Women with aheathy singleton pregnancy in spontaneous or induced labor at term .
Exclusion Criteria
- Hypersensitivity/Contraindication to prostaglandins Antepartum hemorrhage Multiple pregnancy Cardiac disease Malpresentation Rhesus- negative mother hypersensitive disorders Severe anaemia(hemoglobin<7g/dl)
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method reduce blood loss during third and fourth stages of labor. 1 year reduce blood loss during third and fourth stages of labor by using misopristol is better than using oxytocin
- Secondary Outcome Measures
Name Time Method the duration of the third stage of labor ,need for oxytocics ,blood transfusion and any adverse effects of the drugs 1 year the duration of the third stage of labor ,needed for oxytocics ,blood transfusion and any adverse effects of the drug will be reduced with mesopristol
Trial Locations
- Locations (1)
AinShamsU
🇪🇬Cairo, Egypt