Randomised, double-blind, placebo controlled study to assess efficacy of topical nicotinamide in the treatment and prevention of actinic keratosis.

Active, not recruiting

• Conditions: Actinic Keratoses; Skin - Dermatological conditions

• Registration Number: ACTRN12607000428460
• Lead Sponsor: Royal prince Alfred ( Provides infrastructural support)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2007-08-22
• Last Update Posted: 13 January 2020

Recruitment & Eligibility

• Status: Active, not recruiting
• Sex: All
• Target Recruitment: 32

Inclusion Criteria

Symmetrically distributed non-hyperkeratotic AKs on face / scalp/ upper limbs.Minimum of 4 AKs in one or more treatment areas.Patients have received no other treatments for AKs within the last month.

Exclusion Criteria

Pregnant or lactating Taking immunosuppressive or photosensitising medications Taking nicotinamide or other vitamin supplements Patients unable to attend for regular follow up Patients with active dermatitis in the treatment areas.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Reduction in total actinic keratosis count at six months compared with baseline count[AK count at baseline and 6 months]

Secondary Outcome Measures

Name	Time	Method
Reduction in total actinic keratosis count[At three months compared with baseline count]