Effects of Plant Extracts on Semen Quality

Not Applicable

Completed

• Conditions: Poor Semen Quality

• Registration Number: NCT01357044
• Lead Sponsor: Horsens Hospital

Brief Summary

this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality. The investigators hypothesize that these plant extracts will improve semen quality.

Detailed Description

Not available

Study Timeline

• Study Start: 2011-05
• Study First Submitted: 2011-05-17
• Study First Submitted QC: 2011-05-19
• Study First Posted: 2011-05-20
• Primary Completion: 2012-12
• Study Completion: 2013-07
• Status Verified: 2014-10
• Last Update Submitted: 2014-10-08
• Last Update Posted: 2014-10-09

Recruitment & Eligibility

• Status: COMPLETED
• Sex: Male
• Target Recruitment: 70

Inclusion Criteria

• Reduced semen quality

Exclusion Criteria

• Total count of motile sperm less than 1 million sperm/ejaculate or more than 200 million sperm/ejaculate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Primary Outcome Measures

Name	Time	Method
Count of motile sperm per ejaculate	Each participant is given plant extract for three months with flanking semen analyses.

Secondary Outcome Measures

Name	Time	Method
Morphology: percentage of morphologically abnormal sperm in the ejaculate	Each participant is given plant extract for three months with flanking semen analyses.	If we find an increase in the primary outcome measure in data from participants receiving plant extracts and not in those receiving placebo tablets, we wish to further investigate whether sperm morphology also improves when consuming the plant extracts, e.g. whether the percentage of abnormal sperm in an ejaculate decreases in the group of participants receiving the active plant extracts

Trial Locations

Locations (1)

Laboratory of Reproductive Biology; 🇩🇰 Horsens, Denmark