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Effects of Plant Extracts on Semen Quality

Not Applicable
Completed
Conditions
Poor Semen Quality
Registration Number
NCT01357044
Lead Sponsor
Horsens Hospital
Brief Summary

this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality. The investigators hypothesize that these plant extracts will improve semen quality.

Detailed Description

Not available

Recruitment & Eligibility

Status
COMPLETED
Sex
Male
Target Recruitment
70
Inclusion Criteria
  • Reduced semen quality
Exclusion Criteria
  • Total count of motile sperm less than 1 million sperm/ejaculate or more than 200 million sperm/ejaculate

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Primary Outcome Measures
NameTimeMethod
Count of motile sperm per ejaculateEach participant is given plant extract for three months with flanking semen analyses.
Secondary Outcome Measures
NameTimeMethod
Morphology: percentage of morphologically abnormal sperm in the ejaculateEach participant is given plant extract for three months with flanking semen analyses.

If we find an increase in the primary outcome measure in data from participants receiving plant extracts and not in those receiving placebo tablets, we wish to further investigate whether sperm morphology also improves when consuming the plant extracts, e.g. whether the percentage of abnormal sperm in an ejaculate decreases in the group of participants receiving the active plant extracts

Trial Locations

Locations (1)

Laboratory of Reproductive Biology

🇩🇰

Horsens, Denmark

Laboratory of Reproductive Biology
🇩🇰Horsens, Denmark

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