NCT01357044CompletedNot Applicable
An Extract of Pomegranate Fruit and Galangal Rhizome Increases the Numbers of Motile Sperm: A Prospective, Randomised, Controlled, Double-Blinded Trial
Conditions
Interventions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Sponsor
- Horsens Hospital
- Enrollment
- 70
- Locations
- 1
- Primary Endpoint
- Count of motile sperm per ejaculate
Study Overview
Brief Summary
this is a prospective randomized placebo-controlled double-blinded trial investigating the effect of plant extracts from Alpinia galanga and Punica granatum on human semen quality. The investigators hypothesize that these plant extracts will improve semen quality.
Study Design
- Study Type
- Interventional
- Allocation
- Randomized
- Intervention Model
- Parallel
- Primary Purpose
- Treatment
- Masking
- Double (Participant, Investigator)
Eligibility Criteria
- Ages
- 18 Years to — (Adult, Older Adult)
- Sex
- Male
- Accepts Healthy Volunteers
- Yes
Inclusion Criteria
- •Reduced semen quality
Exclusion Criteria
- •Total count of motile sperm less than 1 million sperm/ejaculate or more than 200 million sperm/ejaculate
Arms & Interventions
Plant extracts
Active Comparator
Intervention: Extracts of Punica granatum and Alpinia galanga (Dietary Supplement)
Placebo
Placebo Comparator
Intervention: Placebo (Dietary Supplement)
Outcomes
Primary Outcomes
Count of motile sperm per ejaculate
Time Frame: Each participant is given plant extract for three months with flanking semen analyses.
Secondary Outcomes
- Morphology: percentage of morphologically abnormal sperm in the ejaculate(Each participant is given plant extract for three months with flanking semen analyses.)
Investigators
Jens Fedder
Professor
Horsens Hospital
Study Sites (1)
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