Prevalence of Low Bone Mass and Sarcopenia among Thai Adults with Transfusion Dependent Thalassemia

Not Applicable

Recruiting

• Conditions: Transfusion dependent thalassemiaosteoporosissarcopenia; Osteoporosis; osteopenia; low bone mass; sarcopenia; bone mineral density; thalassemia

• Registration Number: TCTR20201008006
• Lead Sponsor: Ratchadaphiseksomphot Endowment Fund

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2020-10-08
• Study Completion: 2020-11-30
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Recruiting
• Sex: All
• Target Recruitment: 116

Inclusion Criteria

Transfusion dependent thalassemia

Exclusion Criteria

Pregnancy
HIV infection
Stem cell transplantation

Study & Design

• Study Type: Observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Prevalence of Low Bone Mineral Density in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion Bone mineral density by Dexa scan

Secondary Outcome Measures

Name	Time	Method
Risk factor of Bone Mineral Density in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion History taking, Blood samples for hormone evaluation,Prevalence of sarcopenia in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion gait speed, hand grip, Whole body scan,Risk factors of sarcopenia in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion History taking, Blood samples for hormone evaluation,Prevalence of fragility fracture in Adults with Transfusion Dependent Thalassemia 3 months after complete inclusion History taking, morphometric vertebral fractures ,Risk factors of fragility fracture in Adults with Transfusion Dependent Thalassemia months after complete inclusion History taking, Blood samples for hormone evaluation