Bipolar Versus Laser Enaculation of Prostate for >80gram Prostate .
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Bipolar TURP , Laser Enucleation in Management of Enlarged Prostate
- Sponsor
- Menoufia University
- Enrollment
- 40
- Locations
- 1
- Primary Endpoint
- compare the efficacy of Bipolar versus Laser enaculation of prostate for >80gram.
- Status
- Recruiting
- Last Updated
- 2 years ago
Overview
Brief Summary
Transurethral resection of the prostate (TURP ) still the gold standerad for surgical management of enlarged prostate .However , many minimally invasive procedures are now in the comparative track with Bipolar resection as Laser enaculation.
Holmium laser prostatectomy was introduced since 1994 . different types of uses by laser were introduced either resection or enaculation with good outcomes and less complications .
One of the most important issues related to large prostate management is the retreatment after Bipolar resection , another issue that prolonged catheter time post resection .
Detailed Description
Transurethral resection of the prostate (TURP ) still the gold standerad for surgical management of enlarged prostate .However , many minimally invasive procedures are now in the comparative track with Bipolar resection as Laser enaculation. Holmium laser prostatectomy was introduced since 1994 . different types of uses by laser were introduced either resection or enaculation with good outcomes and less complications . One of the most important issues related to large prostate management is the retreatment after Bipolar resection , another issue that prolonged catheter time post resection , so , we try to analyze the effect of Laser enaculation of the prostate in comparison to Bipolar resection in prostate more than 80 gm . Aim of the work: Aim of the work is to compare the efficacy of Bipolar versus Laser enaculation of prostate for \>80gram. Patients and Methods: A randomized comparative study will be conducted at Menoufia university hospital , urology department. patients will be selected after informed consent. Inclusion criteria: similar for all patients prostatic volume more than 80 gm , peak urinary flow rate measurement (Qmax) \<15 ml/s, International Prostate Symptom Score (IPSS) of \>8 , postvoid residual (PVR) \<400 ml. Exclusion criteria: Patients with prostate size less than 80gm , urethral stricture, acute urinary tract infection, repeated treatment . Preoperatively, all the patients will undergo thorough process of history taking , clinical examination, and investigations in the form of abdominopelvic and trans rectal ultrasonography , PSA ,urine analysis, urine culture if needed and routine pre-operative lab investigations as (CBC , PT, LFTs, serum creatinine and RBS). The treatment modality chosen for an individual will be randomized . All patients with positive urine culture will be treated by proper antibiotics before the procedures. Peri-operatively , all patients will receive a single shot of pre-operative antibiotic. For the first group patients transurethral resection of prostate For the second group patients Laser enaculation by holmium: YAG laser Postoperatively, patients will undergo IPSS score , flowmetry post operative after 3months .
Investigators
Hossam Kandeel
Yassin Abdel Ghaffar St- from Gamal Abdel Anasar St - Faculty of Medicine.
Menoufia University
Eligibility Criteria
Inclusion Criteria
- •similar for all patients prostatic volume more than 80 gm , peak urinary flow rate measurement (Qmax) \<15 ml/s, International Prostate Symptom Score (IPSS) of \>8 , postvoid residual (PVR) \<400 ml
Exclusion Criteria
- •Patients with prostate size less than 80gm , urethral stricture, acute urinary tract infection, repeated treatment .
Outcomes
Primary Outcomes
compare the efficacy of Bipolar versus Laser enaculation of prostate for >80gram.
Time Frame: 1 year
compare the efficacy of Bipolar versus Laser enaculation of prostate for \>80gram.