Testing the effects of low levels of blood oxygen and movement of the accuracy of portable vital signs monitors

Not Applicable

Completed

• Conditions: Vital sign monitoring; Not Applicable

• Registration Number: ISRCTN61535692
• Lead Sponsor: niversity of Oxford

Brief Summary

2021 Results article in https://pubmed.ncbi.nlm.nih.gov/34524087/ results (added 21/09/2021) 2022 Results article in https://pubmed.ncbi.nlm.nih.gov/35166690/ (added 16/02/2022) 2020 Protocol article in http://dx.doi.org/10.1136/bmjopen-2019-034404 (added 19/07/2023)

Detailed Description

Not available

Study Timeline

• Results First Posted: 1900-01-01
• Study Start: 2019-06-10
• Study Completion: 2022-03-01
• Last Update Posted: 2 August 2023

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 29

Inclusion Criteria

1. Willing and able to give informed consent for participation in the study
2. Men and women aged 18 or over and in generally good health

Exclusion Criteria

1. Allergies to adhesive dressings (such as bio-occlusive dressings or micropore) or local anesthesic (e.g. Lidocaine)
2. Intra-cardiac device (e.g. Permanent pacemaker) or previous wrist arterial line
3. Epilepsy
4. Angina, congenital heart disease or history of severe cardiopulmonary disease
5. History of anaemia (reported in the pre-screening telephone call) or Hb below 100 g/l on first test
6. Resting hypoxaemia (SpO2 <94%) or significant cardiopulmonary disease rendering exposure to alveolar hypoxia unsafe, as determined by the research physician
7. Pregnancy or breastfeeding
8. Clotting disorders and use of antiplatelet or anticoagulant medication (such as Aspirin)
9. Claustrophobia precluding spell in the hypoxic exposure

Study & Design

• Study Type: Observational
• Study Design: Not specified