MedPath

Intervening Early With Neglected Children

Phase 1
Conditions
ADHD
Depression
Conduct Disorder
Interventions
Behavioral: Developmental Education for Families
Behavioral: Attachment and Biobehavioral Catch-up
Registration Number
NCT02093052
Lead Sponsor
University of Delaware
Brief Summary

This study will assess early and middle childhood outcomes of an intervention for neglecting parents that was implemented in the children's infancy. We expect that parents who received the Attachment and Biobehavioral Catch-up Intervention in infancy will be more nurturing and will follow children's lead more than parents who received a control intervention, and that children will show better outcomes in attachment, inhibitory control, emotion regulation, and peer relations than children of parents who received the control intervention.

Detailed Description

Children were randomly assigned to receive the ABC intervention or a control intervention (DEF) in infancy. These two groups, plus a group of low-risk children, will be studied in early and middle childhood. Of interest will be differences in parent and child outcomes that result from the intervention.

Hypothesis 1: Neglected children whose parents received the ABC intervention and low-risk comparison children will show better inhibitory control than neglected children whose parents received the DEF intervention.

Hypothesis 2: Children in the ABC intervention condition and low-risk comparison children will show better emotion regulation than children in the DEF condition.

Hypothesis 3: Children in the ABC intervention condition and comparison children will show less reactive aggression and less hostile attributional bias than children in the DEF condition.

Hypothesis 4: Children in the ABC condition and comparison children will show more normative cortisol production than children in the DEF condition.

Although we expect that sustained changes in parenting are critical for sustained changes in child behaviors, several alternative models will be tested. First, it is possible that when parents change as a result of the intervention in a child's infancy, there are positive outcomes for children regardless of whether the changes in parenting are sustained. If this is the case, early parenting will mediate the effects of the intervention when controlling for later parenting. Second, if concurrent parenting is what is critical to child functioning, current parenting will mediate intervention effects on child outcomes when controlling for early parenting. Third, longitudinal modeling of both parent and child behaviors allows for analysis of cross-lagged associations using structural equation modeling. Such modeling can examine concurrent and transactional associations between parent and child. We can also examine associations between change at behavioral and biological levels.

Longitudinal modeling will be used to examine models of change in parenting behaviors and how those influence child outcomes.

Recruitment & Eligibility

Status
UNKNOWN
Sex
All
Target Recruitment
220
Inclusion Criteria
  • must have been in earlier randomized clinical trial
Exclusion Criteria

Study & Design

Study Type
INTERVENTIONAL
Study Design
PARALLEL
Arm && Interventions
GroupInterventionDescription
Developmental Education for FamiliesDevelopmental Education for FamiliesDevelopmental Education for Families - 10 session intervention that targets cognitive development
Attachment and Biobehavioral Catch-upAttachment and Biobehavioral Catch-upAttachment and Biobehavioral Catch-up - 10 session intervention to enhance nurturance and following the lead
Primary Outcome Measures
NameTimeMethod
Emotion regulationChild age of 36 months

Children will complete emotion regulation tasks (Perfect Circle and Disappointing Gift)

Cortisol productionChild age of 10

Salivary cortisol levels collected at wake-up and bedtime

AttachmentAge 18 months

Attachment assessed through Strange Situation

Child diagnosisChild age of 10

Parents will complete diagnostic interview.

Inhibitory controlChild age of 36 months

DB-DOS- children who successfully do not touch forbidden toys

Peer relationsChild age of 10 years

Social information processing will be assessed through children's responses to videos of peer provocations.

Child aggressionChild age of 10

Children will complete video game that will allow assessment of reactive and proactive aggression.

Secondary Outcome Measures
NameTimeMethod
Parent Attachment Script KnowledgeChild age of 9

Parents' score on Attachment Script Assessment, a narrative technique

Child inhibitory control in middle childhoodChild age 8

Delay task (Flanker). ERP data will be collected.

Child attachment security (self-reported on Kerns' Attachment Inventory)Child age 10

Self-report from child of extent to which he or she can rely on parent

Parental sensitivityChild age of infancy (12-24 months child age)

Parental sensitivity will be assessed through parent-child interactions.

Parent neural activity assessed through event related potentialsChild age 4

Late positive potential - 350-600 ms after onset of stimulus (LPP) in task discriminating infant affect

Child attachment security (narrative measure)Child age 9

Children's score on Attachment Script Assessment, a narrative technique

Autonomic nervous system activityChild age 10

Child Respiratory Sinus Arrhythmia (RSA)

Child brain activityChild age 9

Child brain activation assessed in fMRI

Alpha and theta waveChild age 9

Alpha and theta wave activity in resting state EEG

Round Robin Assessment of Peer RejectionChild age 9

Play groups of unknown peers constituted and video recorded; videos coded at microanalytic level for indices of peer rejection

Parental sensitivity using Parent-Child Interaction Coding SystemChild age 9

Extent to which parent is responsive and attuned in support discussion (coded behaviorally)

Body mass indexAge 4

Proportion of height to weight

Trial Locations

Locations (1)

University of Delaware

šŸ‡ŗšŸ‡ø

Newark, Delaware, United States

Ā© Copyright 2025. All Rights Reserved by MedPath