Management of Uterine Leiomyomata and Adenomyosis
- Conditions
- Abnormal Uterine Bleeding
- Interventions
- Registration Number
- NCT05153928
- Lead Sponsor
- Ahmed Ali Mahmoud
- Brief Summary
1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination
2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma
- Detailed Description
The aim of the present study is:
1. to determine the role of hysteroscopy and guided biopsy to differentiate between submucosal fibroids and adenomyosis confirmed by histopathological examination
2. to evaluate the efficacy of norethisterone in the treatment of symptomatic adenomyosis and leiomyoma
Recruitment & Eligibility
- Status
- UNKNOWN
- Sex
- Female
- Target Recruitment
- 100
- (1) age≥30 years; (4) dysmenorrhea, adenomyosis-associated chronic pain, and/or menorrhagia.
(3) regular menstrual cycles before administration of norethisterone; (4) no other treatment for adenomyosis/leiomyomatosis at least for 3 months biopsies and histopathology for operated patients;
- (1) pregnant and/or breast-feeding women (2) patients with a ovarian neoplasm, benign ovarian cyst including endometrioma, pelvic inflammatory disease or other endocrine diseases.
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Arm && Interventions
Group Intervention Description fibroid cases Norethisterone acetate Norethisterone acetate for 5 months adenomyosis Norethisterone acetate Norethisterone acetate for 5 months
- Primary Outcome Measures
Name Time Method is to evaluate sensitivity and specificity of hysteroscopy in differentiating between uterine adenomyosis and leiomyomatosis 6 months Symptomatic improvement
- Secondary Outcome Measures
Name Time Method
Trial Locations
- Locations (2)
Ahmed Ali
🇪🇬Assiut, Egypt
Maternaty hospital in assiut
🇪🇬Assiut, Egypt