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Clinical Trials/NCT01250184
NCT01250184
Completed
Phase 4

Treatment of Myofascial Pain Syndrome With Lidocaine Injection and Physical Therapy, Alone or in Combination: a Single-blind, Randomized, Controlled Clinical Trial.

Grupo Rehabilitacion en Salud2 sites in 1 country127 target enrollmentMay 2009

Overview

Phase
Phase 4
Intervention
Physical therapy
Conditions
Myofascial Pain Syndrome
Sponsor
Grupo Rehabilitacion en Salud
Enrollment
127
Locations
2
Primary Endpoint
Visual Analogue Scale
Status
Completed
Last Updated
11 years ago

Overview

Brief Summary

Background: Myofascial pain syndrome (MPS) of the shoulder girdle and cervical region is a common musculoskeletal problem that is often chronic or recurrent. It has demonstrated the effectiveness of different treatments such as exercise, injection but not comparing them with each other. The objective of this research was to demonstrate whether lidocaine injection into trigger points combined with a physical therapy program was more effective than each separatetreatment in improving pain, function and quality of life in a group of patients with myofascial pain syndrome (MPS) of the shoulder girdle and cervical region.

Design: Single-blind, randomized, controlled clinical trial with three parallel groups in the departments of physical medicine and rehabilitation of two urban hospitals. There were 127 patients with myofascial pain in the shoulder girdle for more than six weeks in length and pain greater than 40 mm on the visual analog scale (VAS). There were three intervention groups: physical therapy (PT), lidocaine injection (LI), or the combination of both (PT + LI). The primary outcome at one month was the VAS, and the secondary outcomes were measured using the SF36 pain scaleat one and three months.

Keywords: Myofascial pain, trigger points, lidocaine injection, physical therapy.

Detailed Description

We propose a double blind randomized controlled clinical trial, in different health centers in Medellin. The subjects are patients with myofascial trigger points (MTP) in muscles of the shoulder girdle (levator scapulae, trapezius, infraspinatus) diagnosed by neck ans shoulder pain lasting langer than 6 weeks, and that have not received rehabilitation treatment and are not currently taking analgesic medications. We have calculated a sample of 45 patients in each group. The physical and rehabilitation doctors who evaluated the patients and the nurse who assessed the patients were blinded to treatment allocation. Physicians who performed the MTP injection did not participate in the evaluation of primary and secondary outcomes. Physical therapists who conducted the therapeutic exercise program did not participate in the evaluation of primary and secondary outcomes.

Registry
clinicaltrials.gov
Start Date
May 2009
End Date
September 2011
Last Updated
11 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Sponsor
Grupo Rehabilitacion en Salud
Responsible Party
Principal Investigator
Principal Investigator

Luz Helena Lugo Agudelo

Associate Professor

Grupo Rehabilitacion en Salud

Eligibility Criteria

Inclusion Criteria

  • Cervical Pain at least six weeks
  • At least 40 mm in the VAS
  • They cannot been received treatment like physical therapy or analgesics
  • Maximum score of PHQ 16 points

Exclusion Criteria

  • Depression
  • Fibromyalgia
  • Cervical Radiculopathy

Arms & Interventions

Physical Therapy

Twelve sessions, 3 per week.

Intervention: Physical therapy

Lidocaine injection

Blocking the myofascial trigger point (MTP) with lidocaine injection, unique dose.

Intervention: Lidocaine injection

Lidocaine injection + physical therapy

Blocking the Myofascial trigger point (MTP) with lidocaine injection plus a standarized therapeutic exercise program, twelve sessions, 3 per week.

Intervention: Lidocaine injection + physical therapy

Outcomes

Primary Outcomes

Visual Analogue Scale

Time Frame: 12 weeks

VAS with a score of 0-100, where 100 is the value representing the highest degree of pain and 0 the lowest. Successful treatment was defined as a reduction in pain of at least 20% of the previous score on the VAS after 4 weeks of the initial evaluation, or 14 mm on the VAS; this scale is a reliable pain assessment measure that has been validated previously

Secondary Outcomes

  • Quality of Life SF-36(12 weeks)
  • PHQ 9 Function Measured With the Hand Back and Hand Mouth Maneuvers. Complications and Adverse Reactions Need for Rescue Medication(12 weeks)

Study Sites (2)

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