NCT06044961CompletedNot Applicable
Radiomics-based Models for the Prediction of Pathological Response to Neoadjuvant Therapy in Gastric and Gastroesophageal Cancer
Fondazione Policlinico Universitario Agostino Gemelli IRCCS0 sites80 target enrollmentStarted: January 1, 2005Last updated:
Conditions
Trial Snapshot
- Phase
- Not Applicable
- Status
- Completed
- Enrollment
- 80
- Primary Endpoint
- Use of radiomics
Study Overview
Brief Summary
Identifying predictors of response to neoadjuvant therapy in gastric and gastro-oesophageal cancer early in the history of the disease would ensure optimal treatment planning.
The study aims to apply radiomics for the prediction of response to neoadjuvant therapy.
Study Design
- Study Type
- Observational
- Observational Model
- Other
- Time Perspective
- Retrospective
Eligibility Criteria
- Sex
- All
- Accepts Healthy Volunteers
- No
Inclusion Criteria
- •Patients with locally advanced stomach cancer undergoing neoadjuvant chemotherapy and gastrectomy between January 2005 and August 2022
Exclusion Criteria
- •Siewert 1 tumors;
- •Patients who have received neoadjuvant with the addition of a biological drug;
- •Patients who have received radiotherapy;
- •Patients without staging CT scan or with insufficient image quality in terms of phases performed, pixel spacing, slide thickness (mandatorily: > 5 mm) or artefacts.
Outcomes
Primary Outcomes
Use of radiomics
Time Frame: 1 month
Apply radiomics for predicting response to neoadjuvant therapy.
Secondary Outcomes
No secondary outcomes reported
Investigators
Agnes Annamaria
MD
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
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