Prevalence of Vitamin D Deficiency in Pregnant Women and Their Newborns and Their Association With Maternal and Newborns Characteristics
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 396
- 试验地点
- 1
- 主要终点
- Determine maternal and fetal vitamin D level among pregnant women and their newborns in north Jordan
研究概览
简要总结
In Jordan, there are few data about the prevalence of hypovitaminosis D in pregnant women and their newborns and factors that affect their levels. Hence, in this study, investigators will :
- Determine vitamin D levels among newborns born in north Jordan
- Determine vitamin D levels among pregnant women in north Jordan
- Study the association between maternal and infants levels of vitamin D
- Explore the association between maternal and fetal characteristics and maternal and/or fetal vitamin D level
- Study the effect of low fetal vitamin D on newborn anthropometry
- Study the effect of maternal vitamin D supplement use during pregnancy in raising cord serum vitamin D levels
详细描述
This is a cross-sectional study that will be carried out at King Abdullah University Hospital (KAUH). After being approved by the Institutional Review Board (IRB) of KAUH, written informed consents will be obtained from the newborns' mothers.
5 ml of venous blood will be obtained from pregnant women at the time of admission and 3 ml of venous blood will be obtained from the umbilical cord veins of the newborns immediately after their delivery. The quantitative measurement of 25OHD in serum will be performed using ELIZA.
Investigators will determine the means, medians and standard deviations of 25OHD levels among pregnant women and infants in Jordan. In addition, investigators will study the association between maternal and infants levels of 25OHD. Moreover, investigators will investigate the association between maternal level of vitamin D and elective maternal variables including vitamin D supplements during and before pregnancy, sun exposure, age, weight, parity, BMI, & maternal medical problems. In addition, investigators will study the effect of low fetal vitamin D on newborn anthropometry. Finally, investigators will study the effect of maternal vitamin D supplements use during pregnancy in raising cord serum vitamin D levels
研究设计
- 研究类型
- Observational
- 观察模型
- Other
- 时间视角
- Cross Sectional
入排标准
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •All pregnant women who attend to labour ward with singleton alive pregnancies
排除标准
- •women with multiple pregnancies or with dead fetuses
结局指标
主要结局
Determine maternal and fetal vitamin D level among pregnant women and their newborns in north Jordan
时间窗: 5 minutes
Measurement of vitamin D using ELIZA
次要结局
- Study the association between maternal and infants levels of vitamin D. Study factors that affect maternal and fetal vitamin D level(5 months)