CA125 Levels and Other Inflammatory Markers in Laparoscopic Ventral Hernia Repair

Not Applicable

Completed

• Conditions: Hernia
• Interventions: Procedure: Laparoscopic ventral hernia repair

• Registration Number: NCT01323361
• Lead Sponsor: Oslo University Hospital

Brief Summary

The study aims to show variation in CA-125 and other inflammatory markers assumed to be a response to trauma and peritoneal inflammation in the perioperative period of laparoscopic ventral hernia repair

Detailed Description

CA-125 and other inflammatory markers as body temperature, CRP, PCT, leucocytes and neutrophils measured pre- and post-operatively - correlated to trauma size i.e. area of dissection, mesh size, number of fixation points etc.

Study Timeline

• Study First Submitted: 2011-03-24
• Study First Submitted QC: 2011-03-24
• Study First Posted: 2011-03-25
• Study Start: 2011-04
• Primary Completion: 2012-08
• Study Completion: 2012-08
• Status Verified: 2013-01
• Last Update Submitted: 2013-01-25
• Last Update Posted: 2013-01-28

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 10

Inclusion Criteria

• Adults admitted for ventral or incisional hernia repair

Exclusion Criteria

• Loss-of-domain
• ASA above III
• Liver failure
• Abnormal CA-125 prior to surgery

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
Non-immunosupressed	Laparoscopic ventral hernia repair	Normal population

Primary Outcome Measures

Name	Time	Method
Level of variation in inflammatory markers related to "trauma" impact	6 weeks post surgery

Trial Locations

Locations (2)

Sykehuset Innlandet HF; 🇳🇴 Gjøvik, Oppland, Norway

Oslo University Hospital, Rikshospitalet; 🇳🇴 Oslo, Akershus, Norway