Game based therapy for improving hand function after spinal cord injury

Not yet recruiting

• Conditions: Other and unspecified diseases ofspinal cord,

• Registration Number: CTRI/2025/06/088222
• Lead Sponsor: Sri Balaji Action Medical Institute

Brief Summary

This pilot clinical trial will investigate the feasibility and effectiveness of a gamified sensor-based rehabilitation protocol for improving upper extremity motor function in individuals with cervical spinal cord injury . It will be conducted at Sri Balaji Action Medical Institute, New Delhi, India. The study utilizes the PABLO system of Tyromotion company integrating motion sensors and interactive games to promote task specific training over a 5-week intervention period. Participants  will be engaging in structured game based therapy designed to enhance upper limb functions using real-time feedback.The study adopts a one-group pretest-posttest design with 20 participants with ASIA AIS categories A to D with neurological level of injury from C4 to C8. Following outcome measures will be used to assess various outcomes such as GRASSP-II, SCIM-III, UEMS, CUE-Q, and ISCoS QOL dataset. Preliminary findings will assess user acceptability, clinical relevance, and functional improvement, laying the foundation for future controlled trials in neurorehabilitation.

Detailed Description

Not available

Study Timeline

• Last Update Posted: 2025-05-21
• Study Start: 2025-10-06

Recruitment & Eligibility

• Status: Not Yet Recruiting
• Sex: All
• Target Recruitment: 20

Inclusion Criteria

• At least 18 years of age(either male or female) 2.
• Either traumatic or non-traumatic SCI 3.
• Less than 12 months from the injury 4.
• Spinal cord Injury AIS grade A-D, NLI: C4-C8 5.
• Able to tolerate sitting position on a wheelchair for at least 30 mins.
• Able to read and understand either the English or Hindi language.

Exclusion Criteria

• Moderate to severe spasticity at shoulder, elbow, wrist joints (MAS 2- 4) 2.
• Having psychiatric or other neurological disorders other than SCI 3.
• Have extensive fixed contractures in the upper limb of the target hand preventing use of the instrument 4.
• Head injuries causing cognitive or visual impairment 5.
• Unstable episodes of Autonomic Dysreflexia.
• Had uncorrected vision, had pain in the affected upper limb restricting upper limb movement 7.
• Patients having pressure sores.

Study & Design

• Study Type: Interventional
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
1. Graded Redefined Assessment of Strength Sensibility and Prehension GRASSP-II	At baseline (T0) and post intervention at 5 weeks
Upper extremity motor function	At baseline (T0) and post intervention at 5 weeks
2. Capabilities of Upper Extremity Questionnaire CUE-Q	At baseline (T0) and post intervention at 5 weeks
3. International Standards for Neurological Classification of Spinal Cord Injury ISNCSCI(UEMS)	At baseline (T0) and post intervention at 5 weeks

Secondary Outcome Measures

Name	Time	Method
Functional Independence- Spinal Cord Independence Measure SCIM-III	Quality of Life-International spinal cord society (ISCoS) QOL basic dataset V 1.0

Trial Locations

Locations (1)

Sri Balaji Action Medical Institute; 🇮🇳 West, DELHI, India

Sri Balaji Action Medical Institute

🇮🇳West, DELHI, India

Sunpreet Singh Hanspal

Principal investigator

9711018421

sunpreetsingh055@gmail.com