Comparison of the Effects of TIVA vs VIMA on Content of GSK-3beta in Leucocytes in On-pump Patients: a Randomized Clinical Trial
试验速览
- 阶段
- 4 期
- 状态
- 终止
- 发起方
- 入组人数
- 10
- 试验地点
- 1
- 主要终点
- Gsk-3beta base line content
研究概览
简要总结
Assessment of GSK-3beta contents in leukocytes in on-pump cardiosurgical patients receiving either volatile or intravenous anesthesia
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Diagnostic
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 80 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •elective on-pump CABG
排除标准
- •re-operation
研究组 & 干预措施
Combi
Patiens receiving total intravenous induction and volatile anesthesia
干预措施: Sevoflurane (Drug)
Combi
Patiens receiving total intravenous induction and volatile anesthesia
干预措施: Propofol (Drug)
VIMA
Patiens receiving volatile induction and maitenance of anesthesia
干预措施: Sevoflurane (Drug)
TIVA
Patiens receiving total intravenous anesthesia based on propofol
干预措施: Propofol (Drug)
结局指标
主要结局
Gsk-3beta base line content
时间窗: base line
Gsk-3beta content after induction
时间窗: 20 minutes after tracheal intubation
Gsk-3beta content after surgery
时间窗: immediately after surgery
次要结局
未报告次要终点
研究者
Valery V. Likhvantsev, Professor
senior researcher, Moscow Regional Research and Clinical Institute Moniki n.a. M.F. Vladimirskiy
Moscow Regional Research and Clinical Institute (MONIKI)