Central Lymphoma Repository Tissue Procurement Protocol for Relapse or Recurrent Disease
Overview
- Phase
- Not Applicable
- Intervention
- Not specified
- Conditions
- Lymphoma
- Sponsor
- SWOG Cancer Research Network
- Enrollment
- 32
- Locations
- 82
- Primary Endpoint
- Acquisition of snap-frozen lymphoma tissues
- Status
- Completed
- Last Updated
- 12 years ago
Overview
Brief Summary
RATIONALE: Collecting and storing samples of tissue from patients with non-Hodgkin lymphoma to study in the laboratory may help the study of cancer in the future.
PURPOSE: This laboratory study is collecting and storing tissue samples from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial.
Detailed Description
OBJECTIVES: * Acquire fresh snap-frozen lymphoma tissue from patients with relapsed or recurrent non-Hodgkin lymphoma after treatment on a Southwest Oncology Group (SWOG) clinical trial. * Establish a standard set of procedures for routine acquisition, banking, and study of lymphoma tissues within the SWOG. * Use repository tissue to establish clinical correlations via presently activated phenotyping studies and future projected molecular studies assessing specimen DNA and RNA status. * Examine the biology of therapy failure in relationship to changes in pretreatment and post-treatment immunophenotypic data. OUTLINE: This is a multicenter study. Tissues collected at biopsy are snap-frozen and archived for future molecular and genetic studies. PROJECTED ACCRUAL: Not specified
Investigators
Eligibility Criteria
Inclusion Criteria
- Not provided
Exclusion Criteria
- Not provided
Outcomes
Primary Outcomes
Acquisition of snap-frozen lymphoma tissues
Time Frame: July 2011