Effects of acute and one month ingestion of biologically aged Andalusian wines on endothelial functio

Completed

• Conditions: Arteriosclerosis and endothelial function; Circulatory System; Atherosclerosis

• Registration Number: ISRCTN01319643
• Lead Sponsor: Spanish Foundation for the Wine and Nutrition Research (Fundación para la Investigación del Vino y Nutrición FIVINN) (Spain)

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Start: 2013-04-23
• Last Update Posted: 13 January 2015

Recruitment & Eligibility

• Status: Completed
• Sex: All
• Target Recruitment: 160

Inclusion Criteria

1. Males and females between 55 and 80 years old without documented cardiovascular disease (ischaemic heart disease ? angina or recent or old myocardial infarction or previous or cerebral vascular accident, peripheral vascular disease) and who have diabetes mellitus or three or more of the following factors:
1.1. Current smoking
1.2. Hypertension
1.3. Hypercholesterolemia [LDL-cholesterol > 160 mg/dl, HDL-cholesterol < 40 mg/dl]
1.4. Overweight or obese (body mass index > 25 kg/m2) and/or
1.5. Family history of premature coronary heart disease
2. Healthy males and females between 20 and 40 years
3. The participant should give signed informed consent

Exclusion Criteria

1. Subjects with a previous history of cardiovascular disease (ischaemic heart disease ? angina or recent or old myocardial infarction, cerebral vascular accident, or peripheral vascular disease)
2. Any severe chronic disease
3. Alcoholism or other toxic abuse

Study & Design

• Study Type: Interventional
• Study Design: Not specified