Plaque Reduction Sesame Oil

Not Applicable

Completed

• Conditions: Gingivitis; Oral Microbial Colonization; Dental Plaque
• Interventions: Other: distilled water; Other: sesame oil

• Registration Number: NCT06327841
• Lead Sponsor: Medical University Innsbruck

Brief Summary

The goal of this clinical trials to learn about potential additives in reducing dental plaque. The main questions it aims to answer is:

• is there a difference in the plaque reducing effect of oil pulling with sesame oil compared to rinsing with distilled water? Participants will rinse with 15 ml of their allocated liquid for 15 min every morning for 8 weeks.

Researchers will compare sesame oil against distilled water to see if there is a difference in the plaque reducing effect.

Detailed Description

Not available

Study Timeline

• Study Start: 2022-06-21
• Primary Completion: 2022-08-18
• Study Completion: 2022-08-18
• Status Verified: 2024-03
• Study First Submitted: 2024-03-18
• Study First Submitted QC: 2024-03-22
• Last Update Submitted: 2024-03-22
• Study First Posted: 2024-03-25
• Last Update Posted: 2024-03-25

Recruitment & Eligibility

• Status: COMPLETED
• Sex: All
• Target Recruitment: 40

Inclusion Criteria

• age ≥ 18 years
• contractual capability
• the presence of ≥ 10 teeth,
• community periodontal index of treatment needs (CPITN) grade 1 or 2

Exclusion Criteria

• missing consent
• community periodontal index of treatment needs (CPITN) grade 0, 3 or 4
• pregnancy or breastfeeding
• systemic diseases or conditions that are associated with an increased risk of infection or necessitate concomitant antibiotic therapy with dental treatment
• mental and behavioral disorders that impede (verbal) communication
• allergy against sesame(oil)
• intake of antibiotics 6 months prior to or during study duration
• intake of medication potentially influencing gingival inflammation or bleeding (e.g. anticoagulants, cortisone)
• infectious diseases (e.g. HIV, hepatitis B or C)
• fixed orthodontic appliances
• ongoing oil pulling or mouth rinsing
• adult guardianship
• insufficient nasal breathing

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: PARALLEL

Arm && Interventions

Group	Intervention	Description
distilled water	distilled water	8 weeks rinsing with distilled water 15ml 15min every morning
sesame oil	sesame oil	8 weeks oil pulling with sesame oil 15ml 15min every morning

Primary Outcome Measures

Name	Time	Method
Rustogi Modified Navy Plaque Index (RMNPI)	first follow up after 4 weeks, full study duration 8 weeks

Secondary Outcome Measures

Name	Time	Method
Gingival Index (GI)	first follow up after 4 weeks, full study duration 8 weeks
Oral Health Impact Profile (OHIP)	first follow up after 4 weeks, full study duration 8 weeks
microbial analysis	first follow up after 4 weeks, full study duration 8 weeks
Interview halitosis, xerostomia	first follow up after 4 weeks, full study duration 8 weeks

Trial Locations

Locations (1)

Medical University; 🇦🇹 Innsbruck, Tyrol, Austria