Comparison of the effects of high doses of prednisolone and ACTH on the treatment of infantile spasms
Phase 2
Recruiting
- Conditions
- Infantile spasm.Other disorders of nervous system in diseases classified elsewhere
- Registration Number
- IRCT20200131046317N1
- Lead Sponsor
- Mashhad University of Medical Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 92
Inclusion Criteria
All patients with infantile spasm within the age range of 2 to 12 month
Abnormal Electroencephalography where seizures started a most one month ago with no control over seizures
Exclusion Criteria
Previous use of corticosteroids or ACTH in any way
Known metabolic cause
Brain structural disorder, active infections, history of hypertension and history of heart and kidney diseases
Study & Design
- Study Type
- interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Seizures status. Timepoint: Two weeks after the commencement of the treatment. Method of measurement: Based on parents' reports.;Electroencephalography. Timepoint: Before treatment and two weeks after commencement of the treatment. Method of measurement: Conducting electroencephalography.
- Secondary Outcome Measures
Name Time Method