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临床试验/CTRI/2011/091/000042
CTRI/2011/091/000042已完成2 期

Study of efficacy of of 4-weeks doxycycline in patients of moderate to severe chronic obstructive pulmonary disease with stable symptoms-a randomized, open-labeled, pilot trial

Govt Medical College0 个研究点目标入组 72 人开始时间: 待定最近更新:

试验速览

阶段
2 期
状态
已完成
发起方
入组人数
72

研究概览

简要总结

暂无简介。

研究设计

研究类型
Interventional

入排标准

入选标准

  • 1.Age > 40 years
  • 2.Smoking history >10 packs years
  • 3.Patients classified as GOLD criteria II and III
  • 4.Ability to perform Pulmonary function tests

排除标准

  • 1.Patient with acute exacerbation (Anthonisen et al) / critically ill patients
  • 2.Patient with moderate/severe exacerbation in last 4 weeks as defined by severity scale proposed by Cazzola et al.
  • 3.Patient with active respiratory disease other than COPD (tuberculosis, lung malignancies, Bronchiectasis, pneumonia, bronchial asthma)
  • 4.Patient with acute systemic/local infection
  • 5.Patient with cardiac disease (CCF, Recent myocardial infarction, Cardiac arrhythmias)
  • 6.Patient with gastrointestinal disorders (Gastro-esophageal reflux disorder, peptic ulcer, Undiagnosed abdominal pain)
  • 7.Patient with renal or hepatic impairment
  • 8.Patient with h/o hypersensitivity to tetracyclines
  • 9.Patient receiving oral corticosteroids

研究者

发起方
Govt Medical College

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