Impact of Moderate Alcohol Use on Hepatitis C Virus (HCV) Progression
Completed
- Conditions
- Hepatic FibrogenesisHepatitis C
- Registration Number
- NCT00205075
- Lead Sponsor
- University of Wisconsin, Madison
- Brief Summary
The purpose of this study is to determine the effect of moderate alcohol intake on liver disease caused by HCV in terms of speed of progression as compared to those not drinking alcohol.
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- COMPLETED
- Sex
- All
- Target Recruitment
- 47
Inclusion Criteria
- Outpatient with HCV who is not receiving or planning treatment but is receiving standard of care monitoring every 3 months and is either abstinent from alcohol or drinking only moderately
Exclusion Criteria
- HIV co-infection
- Treated within the past 6 months
- History (hx) of other liver disease
- Alcohol use greater than 30 g/day or history of binge drinking in the last year
- Decompensated liver disease
Study & Design
- Study Type
- OBSERVATIONAL
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method
- Secondary Outcome Measures
Name Time Method
Related Research Topics
Explore scientific publications, clinical data analysis, treatment approaches, and expert-compiled information related to the mechanisms and outcomes of this trial. Click any topic for comprehensive research insights.
What molecular mechanisms link moderate alcohol consumption to hepatic fibrogenesis in HCV-infected patients?
How does moderate alcohol intake affect the progression of HCV-related liver disease compared to standard-of-care treatments?
Are there specific biomarkers that correlate with alcohol-induced liver fibrosis in individuals with chronic HCV infection?
What are the potential adverse events associated with moderate alcohol consumption in HCV patients and how can they be managed?
What combination therapies or alternative approaches have shown efficacy in mitigating HCV-related fibrosis compared to alcohol moderation strategies?
Trial Locations
- Locations (1)
University of Wisconsin
🇺🇸Madison, Wisconsin, United States
University of Wisconsin🇺🇸Madison, Wisconsin, United States