NCT01758094已完成不适用
Plasma RBP Levels in Patients With Idiopathic Hypogonadotrophic Hypogonadism
Gulhane School of Medicine1 个研究点 分布在 1 个国家目标入组 25 人开始时间: 2008年1月最近更新:
适应症
干预措施
相关药物
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 25
- 试验地点
- 1
- 主要终点
- Retinol binding protein 4, hs-CRP levels in patients with idiopathic hypogonadotrophic hypogonadism
研究概览
简要总结
The aim of the present study was to demonstrate the RBP4 levels, association of RBP4 with insulin resistance and influence of testosterone treatment on this cytokine in patients with idiopathic hypogonadotropic hypogonadism.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 19 Years 至 26 Years（Adult）
- 性别
- Male
- 接受健康志愿者
- 是
入选标准
- •decreased serum testosterone concentration below the normal range (serum T < 300ng/dL), FSH and LH levels within or below the normal range, absence of a pituitary or hypothalamic mass lesions on MRI, presence of gonadotropin response to repetitive doses of GnRH, normal smell test and normal karyotypes
排除标准
- •previous androgen treatment, history of smoking, presence of bilateral anorchia, intellectual deficiency, diabetes mellitus, arterial hypertension or dyslipoproteinemia, medication of any kind and drug abuse. Because of possible confounding effects, patients with other hormone deficiencies were excluded.
研究组 & 干预措施
Hypogonadotropic hypogonadism patients
Treatment naive 25 patients with idiopathic hypogonadotrophic hypogonadism
干预措施: Sustanon 250 mg ampule (Testosterone esters) (Drug)
结局指标
主要结局
Retinol binding protein 4, hs-CRP levels in patients with idiopathic hypogonadotrophic hypogonadism
时间窗: 2008-2012
次要结局
- Effect of testosterone treatment on retinol binding globulin 4 and hs-CRP levels in patients with hypogodotrophic hypogonadism(2008-2012)
研究者
Aydogan Aydogdu
MD
Gulhane School of Medicine
研究点 (1)
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