Do Emotions and Pain Combined Affect Mechanical Pain Thresholds and Other Pain-related Variables
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 180
- 试验地点
- 1
- 主要终点
- Pressure pain thresholds (PPTs)
研究概览
简要总结
The purpose of this study is to investigate if different emotional states could influence mechanical pain thresholds and other pain - related variables such as pain tolerance, pain intensity and pain - related negative affect.
详细描述
Participants will be randomized into 4 different groups watching different short video-clips (2.20 min), while at the same time experience short-lasting, experimentally induced pain. The negative emotions group will watch an uncomfortable short video containing violence and blood, the positive emotions group will watch a video containing a stand-up comedy show, the neutral emotions group will watch a video about how to paint a house, and the control group will just wait for 2.20 min, without any instructions about what to think about. Pressure pain thresholds will be measured with an algometer before and after the video-clip combined with experimental pain interventions.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Parallel
- 主要目的
- Basic Science
- 盲法
- None
入排标准
- 年龄范围
- 19 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Above 18 years of age
- •Fluent in Swedish.
排除标准
- •Pain anywhere in body during the test session
- •Known neurological disease.
研究组 & 干预措施
Negative emotion, positive emotion, neutral emotion, control with experimental pain
The intervention includes either a negatively emotionally valenced video, a positively emotionally valenced video, a neutrally emotionally valenced video and experimental pain from the cold pressor test that are simultaneosly applied.
干预措施: Emotional intervention (Other)
结局指标
主要结局
Pressure pain thresholds (PPTs)
时间窗: For each participant, baseline PPTs are measured, intervention follows and intervention PPTs are measured. This will be conducted at one appointment (30 min) for each participant. Recruitment for single appointments will take place for 18 months.
Pressure pain thresholds will be measured i kPa with a handheld algometer (Somedic AB).
次要结局
- Pain tolerance (time in seconds the left hand is immersed in cold water 1 degree C).(At a single session (30 min), the participant will keep their hand immersed in cold water for as long as possible while watching a video. This time will be measured in seconds. Participants are successively recruited for single appointmentsfor 18 months.)
- Pain intensity on the NRS(The pain intensity will be estimated at every single session appointment (30 min) after the intervention on the NRS (Numerical Rating Scale). The participants will be successively recruited for single session appointments for 18 months.)
- Pain-related negative affect on the NRS-A(Negative affect will be estimated at every single test session (30 min) on the NRS-A (Numerical Rating Scale-Anxiety) directly after the intervention. The participants will be successively recruited for single session appointments during 18 months.)
研究者
Helena Gunnarsson
Dr
Linnaeus University