Dosimetric Evaluation of Breathing Impact on PTV and Adjacent Organ At Risk in Breast Cancer Radiotherapy

Active, not recruiting

• Conditions: Breast Cancer

• Registration Number: NCT07048639
• Lead Sponsor: Superior University

Brief Summary

The study is likely an observational study, possibly retrospective or prospective, involving patients with breast cancer undergoing radiotherapy.

Detailed Description

Patients with breast cancer scheduled for radiotherapy will be selected based on specific inclusion and exclusion criteria.

Patients will undergo imaging studies, such as computed tomography (CT) scans, to define the target volumes and OARs.

The study aims to provide insights into the dosimetric impact of breathing motion on PTV and OARs in breast cancer radiotherapy, which can inform strategies to improve treatment planning and delivery.

Study Timeline

• Study Start: 2025-03-17
• Status Verified: 2025-06
• Study First Submitted: 2025-06-24
• Study First Submitted QC: 2025-06-24
• Last Update Submitted: 2025-06-24
• Study First Posted: 2025-07-02
• Last Update Posted: 2025-07-02
• Primary Completion: 2025-09-01
• Study Completion: 2026-03-01

Recruitment & Eligibility

• Status: ACTIVE_NOT_RECRUITING
• Sex: All
• Target Recruitment: 22

Inclusion Criteria

• Patient of breast cancer.
• age 25-40

Exclusion Criteria

• Patients without breast cancer

Study & Design

• Study Type: OBSERVATIONAL
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
Physician's Global Assessment (PGA) Scale with scoring details	12 Months	The Physician's Global Assessment (PGA) scale is a tool used by physicians to evaluate the overall severity of a patient's disease. It's a subjective assessment, typically on a scale of 0 to 3 or 0 to 4, with higher scores indicating more severe disease activity. The PGA focuses on the overall disease activity, considering both the severity of active manifestations and relevant laboratory results, excluding organ damage and subjective findings unrelated to disease activity.

Trial Locations

Locations (1)

INMOL hospital; 🇵🇰 Lahore, Punjab, Pakistan