Thyroid Dysfunction and Obstetric Complications
试验速览
- 阶段
- 不适用
- 状态
- 撤回
- 试验地点
- 1
- 主要终点
- Prevalence of thyroid dysfunction
研究概览
简要总结
Obstetric complications are common and can be responsible for maternal and foetal morbidity and mortality. Thyroid dysfunction has been identified as a possible cause of obstetric complications.
Many studies have been conducted to estimate the prevalence and define the nature of obstetric complications observed in patients with thyroid dysfunction. However, women with obstetric complications are not systematically screened for thyroid dysfunction and no published study has evaluated the prevalence of thyroid dysfunction in women with an obstetric complication. As no consensus has been reached concerning systematic screening for thyroid dysfunction in pregnant women, the identification of new high-risk populations could possibly result in a change of clinical practice.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- Female
- 接受健康志愿者
- 否
入选标准
- •women attending the emergency room and/or hospitalised or followed for:
- •Spontaneous and/or repeated miscarriage
- •Foetal death
- •Pre-eclampsia
- •Retroplacental haematoma
- •Post-partum haemorrhage
- •Premature delivery
- •who consent to participate in the study.
- •Assessment of these women will include blood samples for a laboratory work-up and anti-thyroid antibodies.
排除标准
- •normal pregnancy
结局指标
主要结局
Prevalence of thyroid dysfunction
时间窗: Day 0
Estimate the overall and individual prevalence of thyroid dysfunction (hypothyroidism, hyperthyroidism and thyroid autoimmunity) in patients with obstetrical accident
次要结局
未报告次要终点