Effect of Intertransverse Process Block on the Quality of Recovery Post-Open Hepatectomy: A Pilot Non-Randomised Study of Intervention
试验速览
- 阶段
- 不适用
- 状态
- 尚未招募
- 入组人数
- 20
- 主要终点
- Quality of Recovery (QOR-15)
研究概览
简要总结
The study aims to assess the analgesic efficacy of the ITPB at the retro-SCTL space in patients undergoing major open hepatectomy surgery. This is assessed by:
Primary Objective:
Primary outcome measure:
● Assessing the quality of recovery 15 (QoR15) score at 24 and 48 hours
Secondary outcome measure:
- Number of anaesthetic and hypoesthetic dermatomes on the ventral and dorsal aspect of the thorax on both the sides at 30 minutes of block completion and during the post anaesthetic room (PACU) discharge
- Assessing the 24-hour area under the curve of postoperative pain numerical rating score (NRS, 0-10) at rest and deep breathing or upon use of triflow.
- Assessing the amount of postoperative morphine (mg) equivalent consumption at 24 and 48 hours
- Time to discharge from High dependency unit (HDU) or Intensive care unit (ICU)
Hypothesis:
The investigators hypothesize that the application of ITPB targeting the retro-SCTL space in patients undergoing open hepatectomy will improve overall quality of recovery and pain score.
研究设计
- 研究类型
- Interventional
- 分配方式
- Na
- 干预模型
- Single Group
- 主要目的
- Treatment
- 盲法
- None
入排标准
- 年龄范围
- 18 Years 至 75 Years（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Adult patients aged 18-75 years of ASA I - III physical status classification undergoing open hepatectomy for benign or malignant liver lesion.
排除标准
- •Patient refusal
- •Patients who are unable to comprehend the QoR15 form
- •Local or systemic infection
- •Coagulopathy leading to absolute contraindication to regional anesthesia
- •Contraindication to local anaesthetics (LA) such as LA allergy
研究组 & 干预措施
Open Hepatectomy Patient receiving the intertransverse process block
干预措施: Intertransverse process block (Procedure)
结局指标
主要结局
Quality of Recovery (QOR-15)
时间窗: 24 and 48 hours
The QoR-15 scale is a global measure of postoperative recovery, with a score ranging from 0 (extremely poor QoR) to 150 (excellent QoR). The QoR-15 has since become the most widely reported measure of patient-assessed QoR after surgery. QoR-15 has no units.
次要结局
- Time to discharge from HDU / ICU(Up to 5 days)
- Dermatomal blockade on Thorax 30 minutes upon block completion(Up to 30 minutes after block completion)
- 24 hours area under curve of postoperative pain score(Up to 24 hours)
- Morphine consumption at 24 and 48 hours postoperatively(At 24 and 48 hours postoperatively)
研究者
Wing Sum Li
Resident
Chinese University of Hong Kong