MedPath

OSKIRA-Asia-1

Phase 2
Conditions
Rheumatoid Arthritis
Registration Number
JPRN-jRCT2080221801
Lead Sponsor
AstraZeneca
Brief Summary

Not available

Detailed Description

Not available

Recruitment & Eligibility

Sex
All
Target Recruitment
Not specified
Inclusion Criteria

Active rheumatoid arthritis (RA) diagnosed after the age of 16
- 6 or more swollen joints and 6 or more tender/painful joints from certain joints in the hands, wrists, arms and knees
- At least one of:
-positive result for rheumatoid factor test, either in the past or currently (blood test)
-x-ray showing bone erosion within the last 12 months
-presence of certain antibodies in the blood (blood test)
- Currently taking methotrexate for at least 6 months (and on a stable dose for at least 6 weeks)

Exclusion Criteria

- Females who are pregnant or breast feeding
- Certain inflammatory conditions (other than rheumatoid arthritis), connective tissue diseases or chronic pain disorders.
- Previously taken, but not responded to, certain biological treatments for rheumatoid arthritis
- High blood pressure that is not controlled by medication
- Low levels of neutrophils in the blood (blood test).

Study & Design

Study Type
Interventional
Study Design
Not specified
Primary Outcome Measures
NameTimeMethod
Secondary Outcome Measures
NameTimeMethod
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