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Clinical Trials/NCT02627040
NCT02627040
Unknown
N/A

A Prospective Randomized Trial of Intertrochanteric Femoral Fractures Treated With a Single Screw Versus a Two-integrated Screw Cephalo-medullary Nail.

Florida Orthopaedic Institute2 sites in 1 country95 target enrollmentNovember 30, 2015

Overview

Phase
N/A
Intervention
Not specified
Conditions
Intertrochanteric Fracture
Sponsor
Florida Orthopaedic Institute
Enrollment
95
Locations
2
Primary Endpoint
Hip Function
Last Updated
6 years ago

Overview

Brief Summary

The main goal of the study is to determine which cephalomedullary nail results in a better functional outcome for the patient with an unstable intertrochanteric hip fracture. Subjects will be randomized to fixation with either a Gamma3 cephalomedullary nail or an InterTan cephalomedullary nail. Outcomes will be reviewed over a 12 month follow-up period.

Detailed Description

Primary Hypotheses: Patients who maintain their initial fracture reduction and subsequent position over time with minimal femoral neck shortening and varus will demonstrate significantly improved functional abilities, including gait and abductor function. Secondary Objective: * Whether radiographic differences in femoral neck shortening and varus collapse translate into a worse functional outcome to the patient. * Whether there are differences in mortality between treatments * Whether there is a time frame follow up after which there is no difference in outcomes. * Evaluate the device used for fracture stabilization as a potentially contributing factor for maintenance of normal or near-normal abductor function and gait. Primary Outcome: The primary outcome will be functional abilities at 3, 6 and 12 months after injury. The following measures of functional ability will be utilized: Methods: This is a prospective, randomized non-blinded study. Patients will be identified as they present to the orthopaedic trauma service of Tampa General Hospital with a qualifying injury to determine their interest in participating in the study. Written informed consent will be obtained prior to initiation of any study procedures. Group A will undergo cephalomedullary nail-based single screw intertrochanteric hip fracture fixation device (Gamma 3 nail). Group B will receive the integrated dual screw intertrochanteric hip fracture fixation device (Intertan nail). Patient outcomes will be analyzed using intention to treat principles. Following randomization assignment, surgeons will all follow the identical described surgical technique, with the only variable being the implant used. Post-operative immobilization and time to weight bearing and rehabilitation protocols will be again identical for all patients regardless of fixation technique.

Registry
clinicaltrials.gov
Start Date
November 30, 2015
End Date
September 2020
Last Updated
6 years ago
Study Type
Interventional
Study Design
Parallel
Sex
All

Investigators

Responsible Party
Sponsor

Eligibility Criteria

Inclusion Criteria

  • Patients surgically treated for an intertrochanteric femur fracture at Tampa General Hospital.
  • Skeletally mature patients over the age of 60; both genders.
  • Community ambulators.

Exclusion Criteria

  • Patients with ipsilateral lower extremity injury
  • Patients under age 60
  • Co-existent, severe knee or back problems
  • Muscle contracture around the knee or hip joint
  • Individuals who have had TKA within 6 months
  • Body mass index (BMI; kg/m2) \>40
  • Suspicious of pathologic fracture (tumor in origin)
  • Pre-op mobility: Non ambulatory; ambulatory indoors with living support
  • Cognitive impairment or dementia
  • Prisoners or impending incarceration

Outcomes

Primary Outcomes

Hip Function

Time Frame: 6 months post-operatively

Hip Function measured with Harris Hip Score.

Secondary Outcomes

  • Hip Pain(6 months post-operatively)
  • Functional outcome(6 months post-operatively)
  • Walking ability(3 months post-operatively)
  • Hip range of motion(6 months post-operatively)

Study Sites (2)

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