Value of Radiomics for the Prediction of Long Term Survival and Local Failure After Stereotactic Radiotherapy (SRT) for Brain Metastases
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 发起方
- 入组人数
- 155
- 试验地点
- 1
- 主要终点
- Sensitive value of 12 months local failure after stereotactic radiotherapy for brain metastases with radiomics
研究概览
简要总结
Published prognostic scores have limitations in prediction of long term survival after stereotactic radiotherapy for brain metastases. Moreover, no validated tools are available for prediction of local failure. The value of radiomics is evaluated in this perspective.
详细描述
Sensitivity is low for prediction of long term survival of currently available prognostic scores for brain metastases. First the current clinical models will be optimized with a new prognostic model and nomogram. Radiomics is a tool to analyze tumor characteristics based on CT and MR images. These tumor characteristics may reflect tumor biology and outcome. Therefore it is investigated if radiomics improves prediction of long term survival after stereotactic radiotherapy for brain metastases. Moreover, the predictive value of radiomics for local failure is investigated.
研究设计
- 研究类型
- Observational
- 观察模型
- Cohort
- 时间视角
- Retrospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •Cerebral metastasized patients
排除标准
- 未提供
结局指标
主要结局
Sensitive value of 12 months local failure after stereotactic radiotherapy for brain metastases with radiomics
时间窗: 1 year
Sensitivity of 12 months local failure after stereotactic radiotherapy for brain metastases with radiomics. Radiomics is a tool to analyze tumor characteristics based on CT and MR images.
Sensitive value of 12 months survival after stereotactic radiotherapy for brain metastases with radiomics
时间窗: 1 year
Sensitivity of 12 months survival after stereotactic radiotherapy for brain metastases with radiomics. Radiomics is a tool to analyze tumor characteristics based on CT and MR images.
次要结局
- Negative predictive value of 12 months survival and local failure after stereotactic radiotherapy for brain metastases with radiomics.(1 year)
- Specificity of 12 months survival and local failure after stereotactic radiotherapy for brain metastases with radiomics.(1 year)
- Positive predictive value of 12 months survival and local failure after stereotactic radiotherapy for brain metastases with radiomics.(1 year)