Emotional Reactivity Training for Obsessive-Compulsive and Related Disorders
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 5
- 试验地点
- 1
- 主要终点
- Savings Inventory Revised Scale (for participants diagnosed with hoarding disorder)
研究概览
简要总结
Obsessive-Compulsive Disorder (OCD) is a chronic and disabling disorder that costs the economy over $2 billion annually and represents a significant public health problem. This study aims to build on our understanding of aberrant emotional processing in OCD. The proposed project tests whether a computerized training aimed to alter emotional processes, can relieve repetitive thoughts and behaviors.
研究设计
- 研究类型
- Interventional
- 分配方式
- Randomized
- 干预模型
- Parallel
- 主要目的
- Supportive Care
- 盲法
- Single (Participant)
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •age 18 years old and older
- •primary diagnosis of OCD
- •sufficient severity of OCD symptoms
- •Stable on psychotropic or other medication
- •capacity to provide informed consent
排除标准
- •psychiatric or medical conditions that make participation unsafe
- •concurrent use of any medications that might increase the risk of participation
- •concurrent Cognitive-Behavioral therapy for OCD
研究组 & 干预措施
Active Training
OCD and hoarding disorder participants will receive active emotional reactivity training (14 sessions) via computer.
干预措施: Computerized Training (Behavioral)
Passive Training
OCD and hoarding disorder participants will receive passive computerized training (14 sessions) via computer.
干预措施: Computerized Training (Behavioral)
结局指标
主要结局
Savings Inventory Revised Scale (for participants diagnosed with hoarding disorder)
时间窗: up to 2 months
The SI-R is a 23-item questionnaire with 3 factor-analytically defined sub-scales for difficulty discarding, excessive clutter, and compulsive acquisition.
Yale-Brown Obsessive Compulsive Scale (for participants diagnosed with OCD)
时间窗: up to 2 months
Improvement in OCD severity is measured by the YBOCS (Yale Brown Obsessive-Compulsive Scale), a gold standard measure of obsessions and compulsions. For the YBOCS the minimum units are 0 and Maximum units on the total scale are 40. The higher the number on the YBOCS, the more severe the symptoms. Response is defined as at least a 35% reduction on the YBOCS.
次要结局
未报告次要终点
研究者
Carolyn Rodriguez
Assistant Professor
Stanford University