Outcome and Factors of Liver Disease
Not Applicable
- Conditions
- Health Condition 1: null- Compensated Cirrhosis
- Registration Number
- CTRI/2019/06/019775
- Lead Sponsor
- Institute of liver and Biliary Sciences
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Open to Recruitment
- Sex
- Not specified
- Target Recruitment
- 166
Inclusion Criteria
1)Age 18 to 75 years
2)Compensated cirrhosis
3)Biopsy proven cirrhosis or LSM > 12.5 Kpa.
Exclusion Criteria
1) Any current or prior clinical decompesnation (ascites, jaundice, encephalopathy or gastrointestinal hemorrhage).
2) Pregnant Women
3) Hepatocellular Carcinoma
4) Known case of severe cardiopulmonary disease
5) Known case of severe Hepato Pulmonary Syndrome
Study & Design
- Study Type
- Observational
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method Development of ascites, jaundice, encephalopathy or gastrointestinal hemorrhage) during the follow up period of 2 yeasTimepoint: 2 Years
- Secondary Outcome Measures
Name Time Method umber of patients develop Hepatic osteodystrophy during follow up period of 2 years. <br/ ><br>Timepoint: 2 Year;Number of patients develop hepatocellular carcinoma (HCC) during follow up period 2 years. <br/ ><br>Timepoint: 2 Year;Number of patients develop Hypersplenism during follow up period of 2 years. <br/ ><br>Timepoint: 2 Year;Number of patients develop Minimal Hepatic Encephalopathy (MHE) during follow up period of 2 years. <br/ ><br>Timepoint: 2 Year;Number of patients develop Pulmonary Syndrome (HPS) during follow up period of 2 years. <br/ ><br>Timepoint: 2 Year;Patients with new onset/progression of esophageal varices during the period of 2 yearsTimepoint: 2 Years;Reduction in portal pressure with more than 20% from baseline at 1 yearTimepoint: 1 Year;Reduction in portal pressure with more than 20% from baseline at 2 year.Timepoint: 2 Year;Reduction in portal pressure with more than 20% from baseline at 6 monthsTimepoint: 6 Months;Survival during the period of 2 years.Timepoint: 2 Year