Revision risk and clinical outcome after one- and two-stage knee arthroplasty in the infectious setting-a retrospective analysis.

• Conditions: T84.5; Infection and inflammatory reaction due to internal joint prosthesis

• Registration Number: DRKS00032009
• Lead Sponsor: Medizinische Hochschule Hannover

Brief Summary

Not available

Detailed Description

Not available

Study Timeline

• Study Completion: 2021-07-25
• Results First Posted: 2021-09-27
• Study Start: 2023-09-15
• Last Update Posted: 19 August 2024

Recruitment & Eligibility

• Status: Complete
• Sex: All
• Target Recruitment: 63

Inclusion Criteria

Male or female patients aged = 18 years.
- Performed one- or two-stage KTEP exchange surgery with preoperatively confirmed diagnosis of periprosthetic infection (Pro Implant Foundation criteria)
- Performed single-stage KTEP exchange surgery with postoperatively confirmed KTEP infection according to the above criteria.

Exclusion Criteria

Insufficient documentation or preoperative as well as perioperative diagnostics for correct classification of periprosthetic infection

Study & Design

• Study Type: observational
• Study Design: Not specified

Primary Outcome Measures

Name	Time	Method
The primary objective of this study is to initially investigate the reinfection rate after exchange surgery of a KTEP with a confirmed diagnosis of infection.

Secondary Outcome Measures

Name	Time	Method
Secondary objectives will be to investigate the revision rate, implant survival and, with sufficient patient numbers, patient satisfaction and subjective joint function by means of questionnaires. Furthermore, other demographic co-factors (age, BMI, etc.) will be investigated with regard to their influence on the re-infection rate.