Population-based Chronic Kidney Disease Cohort at Northern Taiwan

Not Applicable

• Conditions: Chronic Kidney Disease, Population, Community, Multidisciplinary, Education
• Interventions: Behavioral: multidisciplinary renal education

• Registration Number: NCT03004898
• Lead Sponsor: Chang Gung Memorial Hospital

Brief Summary

CKD is a global endemic disease with increased comorbidities and mortality. The prevalence and the incidence of the end-stage renal disease (ESRD) are extremely high in Taiwan. The prevalence of CKD remains high; however, the awareness remains low. Screening of unique risk factor and early diagnosis of CKD can improve outcome. Furthermore, data of renal education deep into the community remains limited. The aims of this study are:

1. Explore risk factors associated with CKD in the community

2. Establish multidisciplinary care model in the community

3. Investigate mechanistic mediators for CKD and multidisciplinary education approached in behavioral , physiological, immune and metabolomics aspects

4. Provide bio-specimen repository for future study

Detailed Description

Not available

Study Timeline

• Study Start: 2013-02
• Study First Submitted: 2016-10-14
• Study First Submitted QC: 2016-12-23
• Study First Posted: 2016-12-29
• Status Verified: 2020-03
• Last Update Submitted: 2020-03-06
• Last Update Posted: 2020-03-10
• Primary Completion: 2024-05

Recruitment & Eligibility

• Status: UNKNOWN
• Sex: All
• Target Recruitment: 10000

Inclusion Criteria

• residents of Northern Taiwan

Exclusion Criteria

• pregnancy women, unwilling to participate

Study & Design

• Study Type: INTERVENTIONAL
• Study Design: SINGLE_GROUP

Arm && Interventions

Group	Intervention	Description
education arm	multidisciplinary renal education	multidisciplinary education: multidisciplinary CKD education involving case management nurse, dietitian, social worker, pharmacists.

Primary Outcome Measures

Name	Time	Method
eGFR < 60 mL/min	through study completion, every 1 year	change of renal function between groups
albuminuria/creatinine ratio >=30	through study completion, every 1 year	change of proteinuria between groups
proteinuria/creatine ratio >=150	through study completion, every 1 year	change of proteinuria between groups

Secondary Outcome Measures

Name	Time	Method
SF-36	through study completion, every 1 year	change of score between groups

Trial Locations

Locations (1)

Department of Nephrology, Chang Gung Memorial Hospital; 🇨🇳 Keelung, Taiwan