NCT05854303招募中不适用
Prospective Evaluation of the Effect of Opioid Cessation on Opioid-Induced Esophageal Dysfunction (OIED)
适应症
试验速览
- 阶段
- 不适用
- 状态
- 招募中
- 发起方
- Mayo Clinic
- 入组人数
- 26
- 试验地点
- 1
- 主要终点
- Number of subjects to have opioid-induced esophageal dysfunction resolution
研究概览
简要总结
The purpose of this study is to evaluate the effect of opioid cessation on opioid-induced esophageal dysfunction (OIED).
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 18 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 否
入选标准
- •- Patients enrolled in the Pain Rehabilitation Center for opioid cessation, with or without esophageal symptoms.
排除标准
- •Inability to provide informed consent.
- •Patients with previous gastroesophageal surgery or pneumatic dilation.
- •Esophageal botulinum toxin injection within the prior 12 months.
- •Esophageal stricture
- •Achalasia types I and II
- •Allergy to Lidocaine or other local anesthetics
- •Subjects on anticoagulation
- •Bilateral nasal obstruction
- •Pregnancy or breast feeding
结局指标
主要结局
Number of subjects to have opioid-induced esophageal dysfunction resolution
时间窗: 4 weeks
Number of subjects to have resolution of opioid-induced esophageal dysfunction
次要结局
- Number of subjects with opioid-induced esophageal dysfunction(4 weeks)
- Number of subjects with dysphagia(4 weeks)
- Number of subjects with chest pain(4 weeks)
研究者
Diana L. Snyder
Principal Investigator
Mayo Clinic
研究点 (1)
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