NCT01025024已完成不适用
Investigation of Genetic Disease Marker Associated With Korean Glaucoma Patients Patients, A Single-nucleotide Polymorphism(SNP)Analysis for Primary Open Angle Glaucoma
适应症
试验速览
- 阶段
- 不适用
- 状态
- 已完成
- 入组人数
- 1,224
- 试验地点
- 1
- 主要终点
- genotyping for the SNP associated with primary open angle glaucoma
研究概览
简要总结
A single-nucleotide polymorphism (SNP) analysis of DNA obtained from peripheral blood of the glaucoma patients and the normal control will be performed to find genetic marker for primary open angle glaucoma.
详细描述
Unrelated Korean subjects who have primary open angle glaucoma were recruited in the current study. Genotyping for various SNP associated with POAG due to the linkage disequilibrium patterns is to be performed. Genotypes would be statistically compared between patients with primary open angle glaucoma and normal control subjects free of any eye diseases.
研究设计
- 研究类型
- Observational
- 观察模型
- Case Control
- 时间视角
- Prospective
入排标准
- 年龄范围
- 30 Years 至 —（Adult, Older Adult）
- 性别
- All
- 接受健康志愿者
- 是
入选标准
- •Clinical diagnosis of primary open angle glaucoma
排除标准
- •Primary open angle glaucoma combined with congenital ocular disease
- •Primary open angel glaucoma combined with other ocular disease
- •Significant systemic disease other than systemic hypertension and diabetes
结局指标
主要结局
genotyping for the SNP associated with primary open angle glaucoma
时间窗: one year
次要结局
- genotyping for rs7961953 and additional SNPs in TMTC2 from other linkage disequilibrium patterns(one year)
研究者
研究点 (1)
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