Phase II study of efficacy and safety of duloxetine for chlonic oxaliplatin-induced peripheral neuropathy in metastatic colorectal cancer
Phase 2
Recruiting
- Conditions
- advanced colorectal cancer
- Registration Number
- JPRN-UMIN000010621
- Lead Sponsor
- Osaka City General Hospital Department of Clinical Oncology
- Brief Summary
Not available
- Detailed Description
Not available
Recruitment & Eligibility
- Status
- Recruiting
- Sex
- All
- Target Recruitment
- 20
Inclusion Criteria
Not provided
Exclusion Criteria
1)having other active malignancies 2) severe complications (uncontrolled diabetes mellitus, interstitial lung disease, pulmonary fibrosis, heart failure ,renal failure, hepatic failure, etc.) 3) having active infections 4) history of severe drug hypersensitivity 5) uncontrollable serious mental problem 7) pregnant or female intend to be pregnant, and male intend to make pregnant. 8) peripheral neuropathy>=Gr2 9)Others
Study & Design
- Study Type
- Interventional
- Study Design
- Not specified
- Primary Outcome Measures
Name Time Method prolongation of period of oxaliplatin treatment
- Secondary Outcome Measures
Name Time Method safety